2485-62-3

Basic information

• Product Name: mecysteine
• Synonyms: mecysteine;Cysteine methyl ester;Cysteine methyl;L-Cys-OMe;L-Cysteine methyl;Methyl cysteinate;methyl L-cysteinate
• CAS NO: 2485-62-3
• Molecular Formula: C₄H₉NO₂S
• Molecular Weight: 135.18476
• EINECS: 219-625-7
• Mol File: 2485-62-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 197.2oC at 760 mmHg
• Flash Point: 73.1oC
• Appearance: /
• Density: 1.163g/cm3
• Vapor Pressure: 0.384mmHg at 25°C
• Refractive Index: 1.492
• PKA: 9.35±0.10(Predicted)
• CAS DataBase Reference: mecysteine(CAS DataBase Reference)
• NIST Chemistry Reference: mecysteine(2485-62-3)
• EPA Substance Registry System: mecysteine(2485-62-3)

Safety Data

• Hazardous Substances Data: 2485-62-3(Hazardous Substances Data)

Usage

Definition

ChEBI: An L-cysteinyl ester resulting from the formal condensation of the carboxylic acid group of L-cysteine with methanol. It is used (as the hydrochloride salt) as a mucolytic for the treatment of respiratory disorders associa ed with productive cough.

InChI:InChI=1/C4H9NO2S/c1-7-4(6)3(5)2-8/h3,8H,2,5H2,1H3/t3-/m0/s1

Upstream product

• 67-56-1 methanol 
• 52-89-1 l-cysteine hydrochloride 
• 95588-67-3 S-<2-(4-Ethoxycarbonylphenylsulfonyl)ethyl>cystein-methylester 
• 52-90-4 L-Cysteine 

Downstream Products

• 2519-89-3 (4R)-2-methyl-4,5-dihydrothiazole-4-carboxylic acid methyl ester 
• 6436-58-4 methyl 2-methyl-4,5-dihydrothiazole-4-carboxylate 
• 127761-77-7 L-2-oxothiazolidine-4-carboxylic acid methyl ester 
• 92506-74-6 (R)-2-(Benzyloxycarbonylamino-methyl)-thiazolidine-4-carboxylic acid methyl ester 
• 92506-74-6 (S)-2-(Benzyloxycarbonylamino-methyl)-thiazolidine-4-carboxylic acid methyl ester 
• 141968-72-1 (R)-1,2,6-Trihydroxy-4,11-dioxo-4,8,9,11-tetrahydro-7H-5,12-dioxa-10-thia-7-aza-benzo[def]chrysene-8-carboxylic acid methyl ester 
• 23094-69-1 corilagin 
• 141968-71-0 C₄₅H₃₃NO₂₇S 
• 92506-79-1 (R)-2-((S)-1-Benzyloxycarbonylamino-3-tert-butoxycarbonyl-propyl)-thiazolidine-4-carboxylic acid methyl ester 
• 13405-60-2 β-glucogallin 
• 81322-27-2 L-4,5-Dihydro-2-(4-nitrobenzoylamino)-4-thiazolcarbonsaeuremethylester 
• 130233-85-1 Helioscopinin B 
• 58970-75-5 (S)-1,2,3-tri-O-galloyl-4,6-O-hexahydroxydiphenoyl-β-D-glucopyranose 
• 81534-38-5 1,2,3-tri-O-galloyl-β-D-glucopyranose 

Relevant articles and documents

Selenols are resistant to irreversible modification by HNO

The discovery of nitric oxide (NO) as an endogenously generated signaling species in mammalian cells has spawned a vast interest in the study of the chemical biology of nitrogen oxides. Of these, nitroxyl (azanone, HNO) has gained much attention for its potential role as a therapeutic for cardiovascular disease. Known targets of HNO include hemes/heme proteins and thiols/thiol-containing proteins. Recently, due to their roles in redox signaling and cellular defense, selenols and selenoproteins have also been speculated to be additional potential targets of HNO. Indeed, as determined in the current work, selenols are targeted by HNO. Such reactions appear to result only in formation of diselenide products, which can be easily reverted back to the free selenol. This characteristic is distinct from the reaction of HNO with thiols/thiolproteins. These findings suggest that, unlike thiolproteins, selenoproteins are resistant to irreversible oxidative modification, support that Nature may have chosen to use selenium instead of sulfur in certain biological systems for its enhanced resistance to electrophilic and oxidative modification.

PROCESS FOR THE PREPARATION OF S-ALKYLCYSTEINES

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Fluorescent and Nonfluorescent Aryl Vinyl Sulfones - Reagents Suitable for Protection and Detection of Thiol Functions

The rate of the addition of primary, secondary, and tertiary thiols to aryl/alkyl vinyl sulfones 1 and 4-7 is investigated by competing reactions and by kinetics.The obtained acid stable 2-(alkyl-/arylthio)ethyl sulfones are cleaved by bases to give the starting material by rates corresponding to the rates of addition.Therefore, selective introduction and selective elimination of different (arylsulfonyl)ethyl protective groups in the same molecule is possible by using different kinetic steering factors. - Application of the fluorescent vinyl sulfones 5, 10, and 11 opens new fields for analysis and synthesis.SH-selective vinyl sulfones and thiophosphinic acid cyanides are "orthogonal" protective groups.