248585-29-7Relevant articles and documents
Method for recovering trans - P-aminocyclohexanol by low-concentration waste liquid
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Paragraph 0028-0042, (2021/09/21)
The invention relates to the technical field of medical chemical raw material recycling, and particularly discloses a method for recovering trans -amino cyclohexanol from low-concentration waste liquid. The method comprises the following steps: adjusting the waste liquor to alkalinity, adding benzaldehyde and stirring, filtering and drying to obtain trans -4 - (benzylidene - amino) - cyclohexanol. The trans -4 - (benzylidene - amino) - cyclohexanol was added to a sulfuric acid solution, and after stirring, the liquid was left standing to obtain trans - p-aminocyclohexanol sulfate aqueous solution. After stirring and decoloring, the alkali content of the filtrate is adjusted to - and after the reaction is stirred, the oil layer is left to stand, and extraction, concentration and purification of the extractant are added to the oil layer to obtain trans 10 - 25% -amino cyclohexanol. To the method, waste liquid discharged in industrial synthesis of ambroxol hydrochloride and alkali waste liquid generated by trans -amino cyclohexanol can be produced, and trans -amino cyclohexanol can be recycled.
Alumina supported synthesis of β-lactams using microwave
Kidwai,Venkataramanan,Kohli
, p. 989 - 1002 (2007/10/03)
N(4-hydroxycyclohexyl)-3-mercapto/cyano-4-arylazetidine-2-one were synthesised from N-(4-hydroxycyclohexyl)-arylaldimine by reacting with ethyl α-mercapto/α-cyanoacetate on basic alumina under microwaves, wherein not only the reaction time has been brough
