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N-benzyl-trans-4-aminocyclohexanol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 162338-03-6 Structure
  • Basic information

    1. Product Name: N-benzyl-trans-4-aminocyclohexanol
    2. Synonyms: N-benzyl-trans-4-aminocyclohexanol
    3. CAS NO:162338-03-6
    4. Molecular Formula:
    5. Molecular Weight: 205.3
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 162338-03-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-benzyl-trans-4-aminocyclohexanol(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-benzyl-trans-4-aminocyclohexanol(162338-03-6)
    11. EPA Substance Registry System: N-benzyl-trans-4-aminocyclohexanol(162338-03-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 162338-03-6(Hazardous Substances Data)

162338-03-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 162338-03-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,2,3,3 and 8 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 162338-03:
(8*1)+(7*6)+(6*2)+(5*3)+(4*3)+(3*8)+(2*0)+(1*3)=116
116 % 10 = 6
So 162338-03-6 is a valid CAS Registry Number.

162338-03-6Relevant articles and documents

Highly chemoselective aerobic oxidation of amino alcohols into amino carbonyl compounds

Sasano, Yusuke,Nagasawa, Shota,Yamazaki, Mai,Shibuya, Masatoshi,Park, Jaiwook,Iwabuchi, Yoshiharu

supporting information, p. 3236 - 3240 (2014/04/03)

The direct oxidation of unprotected amino alcohols to their corresponding amino carbonyl compounds has often posed serious challenges in organic synthesis and has constrained chemists to adopting an indirect route, such as a protection/deprotection strategy, to attain their goal. Described herein is a highly chemoselective aerobic oxidation of unprotected amino alcohols to their amino carbonyl compounds in which 2-azaadamantane N-oxyl (AZADO)/copper catalysis is used. The catalytic system developed leads to the alcohol-selective oxidation of various unprotected amino alcohols, carrying a primary, secondary, or tertiary amino group, in good to high yield at ambient temperature with exposure to air, thus offering flexibility in the synthesis of nitrogen-containing compounds. Strong as an ox: The highly chemoselective aerobic oxidation of unprotected amino alcohols to their corresponding amino carbonyl compounds has been achieved by using 2-azaadamantane N-oxyl (AZADO)/copper catalysis. This catalytic system oxidizes not only alcohols with tertiary amino groups but also those with secondary and primary amines in good to high yield at ambient temperature in air. bpy=2,2-bipyridyl, DMAP=4-(N,N-dimethylamino)pyridine.

A rapid and practical entry into cis-1,4-aminocyclohexanols

Gallou, Fabrice,Han, Bo,Lu, Jiang,Seeger-Weibel, Manuela,Stoessel, Anne-Florence,Allmendinger, Simon

experimental part, p. 1419 - 1422 (2010/05/03)

A selective and practical approach for the formation of cis-1,4-aminocyclohexanol was developed. The key transformation involves a one-pot imine formation/ Lewis acid-directed imine reduction and results in a highly selective attack of the reducing agent. This simple and practical method is easily amenable to large-scale synthesis.

A simple and efficient synthesis of N-substituted cyclohex-3-enamines

Alvarez-Perez, Monica,Marco-Contelles, Jose

experimental part, p. 3649 - 3653 (2010/04/05)

A straightforward preparation of N-substituted cyclohex-3-enamines starting from the commercially available trans-4-aminocyclohexanol hydrochloride is described. Cyclohex-3-enamino-functionalized compounds have proven to be interesting intermediates in me

2(1H)-Quinolinone derivatives as novel anti-arteriostenotic agents showing anti-thrombotic and anti-hyperplastic activities

Koga, Yasuo,Kihara, Yoshito,Okada, Minoru,Inoue, Yoshihiro,Tochizawa, Shirou,Toga, Kazuyuki,Tachibana, Kazue,Kimura, Yukio,Nishi, Takao,Hidaka, Hiroyoshi

, p. 1471 - 1476 (2007/10/03)

In order to search for anti-arteriostenotic agents, a series of 2(1H)- quinolinone derivatives was synthesized and evaluated for anti-thrombotic activity and for anti-hyperplastic activity. From this series, (-)-6-[3-[3- cyclopropyl-3-[(1R,2R)-2-hydroxycycyclohexyl]ureido]propoxy]-2(1H)- quinolinone (1p, OPC-33509) was selected as the best candidate by balancing the efficacy on anti-thrombosis and anti-hyperplasia.

A simple method of preparation of 7-alkyl-7-azabicyclo[2.2.1] heptanes

Hassner, Alfred,Belostotskii, Anatoly M.

, p. 1709 - 1712 (2007/10/02)

Action of triphenylphosphine - carbon tetrachloride on the trans-4-alkylaminocyclohexanols leads to 7-alkyl-7-azabicyclo[2.2.1]heptanes in the good yields. The starting aminoalcohols are easily available from the monoethylene ketal of 1,4-cyclohexanedione and primary amines in a four step process without isolation of intermediates.

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