2490-97-3

Basic information

• Product Name: Aceglutamide
• Synonyms: N-ACETYL GLUTAMINE;N-ACETYL-L-GLN;N-ALPHA-ACETYL-L-GLUTAMINE;L-GLUTAMINE, N2-ACETYL-;L-GLUTAMINE, N-ACETYL-;L-2-ACETAMIDOGLUTARAMIC ACID;ACETYL-L-GLUTAMINE;ACETYL-L-GLUTAMINE, N-
• CAS NO: 2490-97-3
• Molecular Formula: C₇H₁₂N₂O₄
• Molecular Weight: 188.18
• EINECS: 219-647-7
• Product Categories: Amino ACIDS SERIES;Amino Acids;Glutamine [Gln, Q];Ac-Amino Acids;Amino Acids (N-Protected);Biochemistry;N-Acetyl-Amino acid series;Amino Acid Derivatives;Glutamine;Peptide Synthesis;A - H;Amino Acids;Modified Amino Acids;amino acid;ACUTIL-S;amino;API
• Mol File: 2490-97-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 206-208 °C
• Boiling Point: 604.9 °C at 760 mmHg
• Flash Point: 319.6 °C
• Appearance: /Crystalline
• Density: 1.29 g/cm³
• Vapor Pressure: 3.42E-16mmHg at 25°C
• Refractive Index: -12 ° (C=3, H2O)
• Storage Temp.: 2-8°C
• PKA: 3.52±0.10(Predicted)
• Water Solubility: almost transparency
• Merck: 14,25
• BRN: 1727471
• CAS DataBase Reference: Aceglutamide(CAS DataBase Reference)
• NIST Chemistry Reference: Aceglutamide(2490-97-3)
• EPA Substance Registry System: Aceglutamide(2490-97-3)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 2490-97-3(Hazardous Substances Data)

Usage

Description

Aceglutamide is a glutamine derivative with an acetyl group bound at the alpha-amino group. It is a crystalline compound known for its nootropic properties, which means it can enhance cognitive functions such as memory, creativity, and problem-solving abilities.

Uses

Used in Pharmaceutical Industry:
Aceglutamide is used as a nootropic agent for improving cognitive functions. It is particularly beneficial for individuals experiencing memory impairment or cognitive decline, as it can help enhance memory, learning, and overall brain function.
Used in Sports Nutrition:
In the sports nutrition industry, Aceglutamide is used as a cognitive enhancer to support athletes in their training and performance. It can help improve focus, mental clarity, and decision-making skills during high-intensity activities, leading to better overall performance.
Used in Neurological Research:
Aceglutamide is also used in neurological research as a potential therapeutic agent for various neurological disorders. Its nootropic properties make it a promising candidate for the treatment of conditions such as Alzheimer's disease, Parkinson's disease, and other cognitive impairments.
Used in Cosmeceuticals:
In the cosmeceuticals industry, Aceglutamide is used as an ingredient in anti-aging and skin care products. Its ability to improve blood flow and oxygenation to the brain may also contribute to improved skin health and a more youthful appearance.

InChI:InChI=1/C7H12N2O4/c1-4(10)9-5(7(12)13)2-3-6(8)11/h5H,2-3H2,1H3,(H2,8,11)(H,9,10)(H,12,13)/t5-/m0/s1

Upstream product

• 56-85-9 L-glutamine 
• 108-24-7 acetic anhydride 
• 71989-20-3 N₂-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-glutamine 
• 64-19-7 acetic acid 

Downstream Products

• 906537-40-4 (S)-2-acetamido-N₁-((R)-1-((2R,4R)-2-(3-azidopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pentanediamide 
• 906537-66-4 (S)-2-acetamido-N₁-((R)-1-((2R,4S)-2-(3-azidopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pentanediamide 
• 906536-45-6 (S)-2-acetamido-N₁-((R)-1-((2S,4R)-2-(3-azidopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pentanediamide 
• 906537-56-2 (S)-2-acetamido-N₁-((R)-1-((2S,4S)-2-(3-azidopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pentanediamide 
• 906536-12-7 benzyl 2-((2R,4R)-1-((R)-2-((S)-2-acetamido-5-amino-5-oxopentanamido)-3-phenylpropanoyl)-4-(naphthalen-2-ylmethoxy)pyrrolidine-2-carboxamido)ethylcarbamate 
• 910568-09-1 {3-[(S)-1-[(R)-2-((S)-2-Acetylamino-4-carbamoyl-butyrylamino)-3-(4-fluoro-phenyl)-propionyl]-4-((S)-1-methylcarbamoyl-2-naphthalen-2-yl-ethyl)-3-oxo-piperazin-2-yl]-propyl}-carbamic acid benzyl ester 
• 56-85-9 L-glutamine 
• 56159-64-9 methyl 2-acetamido-5-amino-5-oxopentanoate 
• 98-79-3 L-Pyroglutamic acid 

Relevant articles and documents

A fundamental study of amadori rearrangement products in reducing sugar-amino acid model system by electrospray ionization mass spectrometry and computation

It is crucial to characterize Amadori rearrangement products (ARPs) formed in the early stage of Maillard reaction, one of the most important modifications in food science. We setup a reaction model system using six selected amino acids (arginine, asparagines, glutamine, histamine, lysine and tryptophan) and their N-terminal acetylated forms with different reducing sugars for a fundamental study of Amadori rearrangement products. The effects on forming Amadori rearrangement products were studied by using electrospray ionization mass spectrometry (ESI-MS). The reaction rate was affected by reaction temperature, reaction time, property of sugars and amino acids and the fragmentation mechanism of Amadori rearrangement products was illustrated by tandem MS (MS2) with collision-induced dissociation. The proposed fragmentation mechanism of Amadori rearrangement products in MS2 was provided based on MS2 data and it was supported by their computational data of density functional theory (DFT) at the B3LYP/6-31++G(d,p) level.