2491-96-5

Upstream product

• 69-72-7 salicylic acid 
• 1441-87-8 salicyloyl chloride 
• 936-02-7 2-Hydroxybenzoylhydrazine 
• 63218-91-7 1-[(2-Hydroxy-phenyl)-methylsulfanyl-methylene]-piperidinium; iodide 
• 3232-36-8 salicylidene salicylhydrazide 
• 90-02-8 salicylaldehyde 
• 119-36-8 methyl salicylate 
• 2032-48-6 1-(o-hydroksy)tiobenzoilopiperydyna 
• 111997-47-8 2-(o-Hydroxy-α-piperidinobenzylidene)salicylohydrazide 
• 23647-78-1 N,N'-bis(salicyloyl)hydrazine 

Downstream Products

• 955093-00-2 2,5-bis[2-(N,N-diethyl-1'-oxopropylamide)phenyl]-1,3,4-oxadiazole 
• 1236049-14-1 2,3,14,15-dibenzo-4,7,10,13,19-pentaoxa-17,18-diazabicyclo[14.2.1]nonadeca-16,18-diene 
• 1346704-67-3 2,5-bis(2-(4-cyanobenzyloxy)phenyl)-1,3,4-oxadiazole 
• 1346704-68-4 2,5-bis(2-(3-cyanobenzyloxy)phenyl)-1,3,4-oxadiazole 
• 1384983-23-6 C₂₆H₃₀N₂O₇ 

Relevant academic research and scientific papers

Synthesis and luminescence properties of 1,3,4-oxadiazole acetamide derivatives and their rare earth complexes

A series of 1,3,4-oxadiazole acetamide derivatives have been designed and synthesized, and their complexes with Eu(III) and Tb(III) were also prepared. The luminescence properties of the target complexes were investigated, and the results indicated that a

Synthesis of new 1,3,4-oxadiazoles as antibacterial and antifungal agents

A new series of 1,3,4 oxadiazoles (2a-j) were prepared by reacting 2-hydroxybenzo hydrazide (1) with substituted aromatic acids in presence of phosphorous oxychloride. All the newly synthesized compounds were evaluated for their in-vitro antibacterial and antifungal activities. The structures of new compounds were assigned on the basis of 1H NMR, IR, Mass spectral data and elemental analysis.

Electrochemical oxidation of aldehyde-N-arylhydrazones into symmetrical-2,5-disubstituted-1,3,4-oxadiazoles

A convenient, efficient and one-pot synthesis of chemically and pharmaceutically interesting symmetrical-2,5-disubstituted-1,3,4-oxadiazoles is reported. The protocol involves anodic oxidation of aldehyde-N-arylhydrazones in anhyd. MeCN-LiClO4. Constant potential electrolysis carried out in an undivided cell and platinum electrodes leads to the formation of the corresponding oxadiazoles under ambient condition and the mechanism was deduced from voltammetry studies. The reaction proceeded smoothly with high atom economy. Springer Science+Business Media Dordrecht 2013.

Electrosynthesis and screening of novel 1,3,4-oxadiazoles as potent and selective antifungal agents

The electrochemical oxidation of aldehyde-N-aroylhydrazone has been studied in the presence of NaClO4 as supporting electrolyte in MeOH solution using cyclic voltammetry and controlled potential electrolysis. The results indicate that intramolecular cyclization of aldehyde-N-aroylhydrazone has been successfully performed at a platinum electrode in an undivided cell with good yields of the corresponding 1,3,4-oxadiazoles at ambient conditions. The reaction products were characterized by spectroscopic methods and a mechanism was deduced from voltammetry studies. The antifungal activity of the synthesized compounds was evaluated on Fusarium oxysporum, Alternaria solani, Candida albicans and Aspergillus niger. The results revealed that all the synthesized compounds have significant antifungal activity against the tested fungi. Among the synthesized derivatives 7b, 7d, 7g, 7h, 7i, 7j and 7r were found to be the most effective antifungal compounds. The Royal Society of Chemistry 2013.

Synthesis and evaluation of some novel substituted 1,3,4-oxadiazole and pyrazole derivatives for antitubercular activity

A series of 1,3,4-oxadiazole and pyrazole derivatives have been synthesized and evaluated for antitubercular activity. All the structures of the newly synthesized compounds have been supported by IR,1H NMR, MS and CHN analysis. All the compounds have shown promising antitubercular activity when compared with the standard drug Streptomycin.

Synthesis and properties of iridium complexes based 1,3,4-oxadiazoles derivatives

A series of iridium complexes with 2,5-diaryl-[1,3,4]-oxadiazole ligands were synthesized and their electrochemical, photophysical, and electroluminescent (EL) properties studied. It was found that electron-withdrawing or donating substituents on the phenyl ring affected the emission maxima. Complex 3, iridium(III) bis(2,5-bis-(2-hydroxyphenyl)-[1,3,4]oxadiazolato-C2′,N3) (acetyl acetonate), was characterized by single-crystal X-ray structural determination. Three organic light emitting diodes devices were fabricated, which showed stable green-yellow luminescence.

Synthesis and structural studies of novel 1,3,4-oxadiazolophanes

The title compounds have been prepared in moderate yields from compound 2a/2b as starting unit, which are obtained, in good yields by one-step process in high purity. Interesting results have been obtained when the cyclisation products were studied for structural analysis. The title compounds are also studied for their use as PTC agents.

An efficient one pot synthesis of 1,3,4-oxadiazoles

Various 1,3,4-oxadiazoles have been synthesized in excellent yields by BF3·Et2O promoted cyclodehydration of 1,2-diacyl and diaroyl hydrazines prepared in situ from corresponding acid chlorides and hydrazine.

Rapid synthesis of 2,5-disubstituted 1,3,4-oxadiazoles under microwave irradiation

A number of symmetrically 2,5-disubstituted 1,3,4-oxadiazoles are quickly prepared by the reaction of aromatic acids with hydrazine dihydrochloride in a mixture of orthophosphoric acid and phosphorus pentoxide under microwave irradiation.

A new synthesis of symmetrical 2,5-disubstituted 1,3,4- oxadiazoles

Several new 2,5-disubstituted 1,3,4-oxadiazoles have been synthesized in good yields by reaction of aromatic acids with hydrazine dihydrochloride in a mixture of orthophosphoric acid, phosphorus pentoxide and, in general, with addition of phosphorus oxychloride to the reaction mixture. The structures of new oxadiazoles derivatives were confirmed by analytical and spectral data.