249284-75-1Relevant academic research and scientific papers
New concise asymmetric total synthesis of (+)-desoxoprosophylline and prosophylline
Yang, Cuifen,Liao, Lixin,Xu, Yiming,Zhang, Hongxing,Xia, Peng,Zhou, Weishan
, p. 2311 - 2318 (2007/10/03)
Asymmetric total syntheses of (+)-desoxoprosophylline 1 and prosophylline 2 from 1-(α-furyl)-2-phenylmethoxy-N-tosylethylamine 3 were accomplished in 10 steps with an overall yield of 4% and in nine steps with an overall yield of 11%, respectively. The oxidation of 3 to dihydropyridone was used as the key step.
