249297-75-4

Upstream product

• 7252-83-7 1-bromo-2,2-dimethoxyethane 
• 249297-73-2 (R)-C-benzofuran-2-yl-C-4-chlorophenyl-methylamine 
• 226699-02-1 (S)-1-(4-chlorophenyl)-2-propynylamine 
• 226698-95-9 (+/-)-1-(4-chlorophenyl)-2-propynylamine 
• 533-58-4 2-Iodophenol 

Downstream Products

• 249297-77-6 N-[benzofuran-2-yl-(4-chloro-phenyl)-methyl]-N-(2,2-dimethoxy-ethyl)-formamide 

Relevant academic research and scientific papers

Chiral azole derivatives, 31. Synthesis of the enantiomers of the potent aromatase inhibitor 1-[2-benzofuranyl(4-chlorophenyl)methyl]-1H-imidazole

Starting from (+)- and (-)-1-(4-chlorophenyl)-2-propynylamine, in turn obtained by CAL-mediated kinetic resolution of the corresponding racemate, a stereoselective synthesis of both enantiomers of the title compound has been achieved.