24953-74-0

Usage

Type of compound

Dimethyl ester of vanillic acid

Natural occurrence

Found in certain plant species

Potential properties

a. Antioxidant
b. Anti-inflammatory

Applications

a. Synthesis of pharmaceuticals
b. Synthesis of agricultural chemicals
c. Food industry (due to natural origins and beneficial properties)
d. Cosmetic industry (due to natural origins and beneficial properties)

Upstream product

• 24953-73-9 Dimethyl 3,5-dimethoxyphthalate 
• 16807-60-6 3-methoxycyclohex-2-en-1-one 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 67609-51-2 3,5-Dihydroxy-phthalic acid dimethyl ester 
• 77-78-1 dimethyl sulfate 
• 63559-15-9 (5,5-dimethylcyclohexa-1,3-diene-1,3-diyl)bis(oxy)bis(trimethylsilane) 

Downstream Products

• 24953-75-1 3-hydroxy-5-methoxy-phthalic acid 
• 95695-09-3 5-Methoxy-3-(tetrahydro-pyran-2-yloxy)-phthalic acid dimethyl ester 
• 116502-80-8 3-hydroxy-5-methoxy-1,2-benzenedimethanol 
• 95695-31-1 5-Methoxy-3-methoxymethoxy-phthalic acid dimethyl ester 
• 911797-71-2 5-Methoxy-3-methoxymethoxy-benzene-1,2-dicarbaldehyde 
• 95695-42-4 (2-Hydroxymethyl-4-methoxy-6-methoxymethoxy-phenyl)-methanol 
• 95695-10-6 [2-Hydroxymethyl-4-methoxy-6-(tetrahydro-pyran-2-yloxy)-phenyl]-methanol 
• 911794-92-8 3-Hydroxy-5-methoxy-4-(2,5,5,8a-tetramethyl-3,4,4a,5,8,8a-hexahydro-naphthalen-1-ylmethyl)-benzene-1,2-dicarbaldehyde 
• 95695-11-7 2-[2,3-Bis-(tert-butyl-dimethyl-silanyloxymethyl)-5-methoxy-phenoxy]-tetrahydro-pyran 

Relevant academic research and scientific papers

A Negishi cross-coupling reaction enables the total synthesis of (+)-stachyflin

We present a full account on the development of the total synthesis of the antiviral meroterpenoid (+)-stachyflin. The decalin subunit is rapidly accessed by an exo-selective Diels–Alder reaction, whereas the isonindolinone was synthesized via a highly efficient and practical de novo route starting from dimedone. A challenging sp2–sp3 Negishi cross-coupling reaction enabled construction of the crucial C15–C16 bond that connects the arene with the decalin subunit. For the final installation of the cis-decalin framework, a Lewis acid-catalyzed cyclization was applied.

AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION

This invention provides amine-linked C3-glutarimide Degronimers and Degrons for therapeutic applications as described further herein, and methods of use and compositions thereof as well as methods for their preparation.