249647-26-5

Basic information

• Product Name: (3-BroMo-4-iodo-phenyl)-Methanol
• Synonyms: (3-BroMo-4-iodo-phenyl)-Methanol;3-bromo-4-iodobenzenemethanol
• CAS NO: 249647-26-5
• Molecular Formula: C₇H₆BrIO
• Molecular Weight: 312.93041
• Mol File: 249647-26-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3-BroMo-4-iodo-phenyl)-Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (3-BroMo-4-iodo-phenyl)-Methanol(249647-26-5)
• EPA Substance Registry System: (3-BroMo-4-iodo-phenyl)-Methanol(249647-26-5)

Safety Data

• Hazardous Substances Data: 249647-26-5(Hazardous Substances Data)

Usage

General Description

"(3-Bromo-4-iodo-phenyl)-Methanol" is a chemical compound that consists of a phenyl ring substituted with both bromine and iodine atoms, as well as a methanol group attached to the phenyl ring. It is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various molecules and pharmaceutical compounds. The presence of both bromine and iodine atoms in the molecule makes it a versatile reagent for a wide range of chemical reactions, and its use in medicinal chemistry is of particular interest due to the potential biological activities associated with the bromo and iodo substituents. Additionally, the presence of the methanol group allows for further modification and functionalization of the molecule, making it a valuable tool in chemical and pharmaceutical research.

Upstream product

• 1261470-90-9 C₇H₃BrClIO 
• 106896-49-5 methyl 4-amino-3-bromobenzoate 
• 619-44-3 methyl 4-iodobenzoate 
• 249647-24-3 3-bromo-4-iodobenzoic acid methyl ester 
• 249647-25-4 3-bromo-4-iodobenzoic acid 

Downstream Products

• 249647-29-8 3-bromo-4-iodobenzyl iodide 
• 1379928-92-3 (4-(4-(3,4-dimethylphenyl)-3-(m-tolyl)but-1-yn-1-yl)-3-(thiophen-2-yl)phenyl)methanol 
• 1379928-94-5 4-(4-(3,4-dimethylphenyl)-3-(m-tolyl)but-1-yn-1-yl)-3-(thiophen-2-yl)benzaldehyde 
• 1379928-95-6 (4-(4-(3,4-dimethylphenyl)-3-(m-tolyl)but-1-yn-1-yl)-3-(furan-2-yl)phenyl)methanol 
• 1379928-99-0 4-(4-(3,4-dimethylphenyl)-3-(m-tolyl)but-1-yn-1-yl)-3-(furan-2-yl)benzaldehyde 
• 1379928-89-8 (3-bromo-4-(4-(3,4-dimethylphenyl)-3-(m-tolyl)but-1-yn-1-yl)phenyl)methanol 
• 1357614-70-0 (E/Z)-3-bromo-4-iodobenzaldehyde oxime 
• 1357614-71-1 3-(3-bromo-4-iodophenyl)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole 

Relevant articles and documents

The Discovery and Structure-Activity Evaluation of (+)-Floyocidin B and Synthetic Analogs

Tuberculosis represents one of the ten most common courses of death worldwide and the emergence of multidrug-resistant M. tuberculosis makes the discovery of novel anti-tuberculosis active structures an urgent priority. Here, we show that (+)-floyocidin B representing the first example of a novel dihydroisoquinoline class of fungus-derived natural products, displays promising antitubercular hit properties. (+)-Floyocidin B was identified by activity-guided extract screening and its structure was unambiguously determined by total synthesis. The absolute configuration was deduced from a key synthesis intermediate by single crystal X-ray diffraction analysis. A hit series was generated by the isolation of further natural congeners and the synthesis of analogs of (+)-floyocidin B. Extensive biological and physicochemical profiling of this series revealed first structure-activity relationships and set the basis for further optimization and development of this novel antitubercular scaffold.

ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS

This invention recites isoxazoline substituted azetidine derivatives of Formula (1) stereoisomers thereof, veterinarily acceptable salts thereof, compositions thereof, and their use as a parasiticide in mammals and birds. R1a, R1b, R1c, R2, R3, R4, R6, and n are as described herein.