24966-30-1

Basic information

• Product Name: 2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile
• Synonyms: a-Acetyl-1,3-benzodioxole-5-acetonitrile;2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile
• CAS NO: 24966-30-1
• Molecular Formula: C₁₁H₉NO₃
• Molecular Weight: 203.19406
• Mol File: 24966-30-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 307.4±42.0 °C(Predicted)
• Appearance: /
• Density: 1.288±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile(24966-30-1)
• EPA Substance Registry System: 2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile(24966-30-1)

Safety Data

• Hazardous Substances Data: 24966-30-1(Hazardous Substances Data)

Usage

General Description

2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile is a chemical compound with the molecular formula C12H7NO4. It is a nitrile derivative containing a benzodioxole ring system. 2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile is used in the field of organic synthesis and pharmaceutical research, as it has potential biological activities and can be utilized as a building block for the synthesis of various bioactive molecules. Its structure and properties make it an interesting target for medicinal chemistry and drug development, and further research into its potential applications is ongoing.

Upstream product

• 20850-43-5 5-(chloromethyl)-1,3-benzodioxole 
• 495-76-1 piperonol 
• 120-57-0 piperonal 
• 141-78-6 ethyl acetate 
• 4439-02-5 3,4-methylenedioxyphenylacetonitrile 

Downstream Products

• 25375-48-8 4,4a-dihydro-3H,6H-5,11b-ethano[1,3]dioxolo[4,5-j]phenanthridin-3-ol 

Relevant articles and documents

Stereoselective C?C Oxidative Coupling Reactions Photocatalyzed by Zwitterionic Ligand Capped CsPbBr3 Perovskite Quantum Dots

Semiconductor quantum dots (QDs) have attracted tremendous attention in the field of photocatalysis, owing to their superior optoelectronic properties for photocatalytic reactions, including high absorption coefficients and long photogenerated carrier lifetimes. Herein, by choosing 2-(3,4-dimethoxyphenyl)-3-oxobutanenitrile as a model substrate, we demonstrate that the stereoselective (>99 %) C?C oxidative coupling reaction can be realized with a high product yield (99 %) using zwitterionic ligand capped CsPbBr3 perovskite QDs under visible light illumination. The reaction can be generalized to different starting materials with various substituents on the phenyl ring and varied functional moieties, producing stereoselective dl-isomers. A radical mediated reaction pathway has been proposed. Our study provides a new way of stereoselective C?C oxidative coupling via a photocatalytic means using specially designed perovskite QDs.

PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL COMPOUNDS

A compound of formula (I) or a pharmaceutically acceptable salt thereof, useful in therapy, in particular in the treatment of a viral infection.

Oxidative aromatic C-O bond formation: synthesis of 3-functionalized benzo[b]furans by FeCl3-mediated ring closure of a-Aryl ketones

A variety of 3-functionalized benzo[b]furans were achieved by way of a FeCl3-medlated Intramolecular cyclization of electron-rich a-aryl ketones. The alkoxy substituent on the benzene ring In the substrates was essential for an efficient cyclization to occur. This novel method allows the construction of benzo[b]furan rings by joining the O-atom on the side chain to the benzene ring via direct oxidative aromatic C-O bond formation.