249744-04-5

Basic information

• Product Name: 3-(2-oxo-3-triphenylphosphoranediylpropyl)-4(3H)-quinazolinone
• Synonyms: 3-(2-oxo-3-triphenylphosphoranediylpropyl)-4(3H)-quinazolinone
• CAS NO: 249744-04-5
• Molecular Weight: 462.488
• Mol File: 249744-04-5.mol

Chemical Properties

• CAS DataBase Reference: 3-(2-oxo-3-triphenylphosphoranediylpropyl)-4(3H)-quinazolinone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-oxo-3-triphenylphosphoranediylpropyl)-4(3H)-quinazolinone(249744-04-5)
• EPA Substance Registry System: 3-(2-oxo-3-triphenylphosphoranediylpropyl)-4(3H)-quinazolinone(249744-04-5)

Safety Data

• Hazardous Substances Data: 249744-04-5(Hazardous Substances Data)

Upstream product

• 491-36-1 4-Hydroxyquinazoline 
• 5632-37-1 1-(quinazolin-4(3H)-on-3-yl)-propan-2-one 
• 99851-81-7 3-(3-bromo-2-oxopropyl)-4(3H)-quinazolinone 
• 491-36-1 4-quinazolinol 
• 13605-66-8 1-chloro-3-(triphenylphosphoranylidene)acetone 

Downstream Products

• 249744-05-6 3-(8-benzyloxycarboxamido-2-oxo-3-octenyl)-4(3H)-quinazolinone 
• 249744-06-7 3-[2-oxo-3-(1-benzyloxycarbonyl-2-piperidyl)propyl]-4(3H)-quinazolinone 

Relevant articles and documents

A convergent total synthesis of (+)-febrifugine

Febrifugine was synthesized in ten steps from N-Boc 4-aminobutan-1-ol by a convergent approach. Georg Thieme Verlag Stuttgart.

Synthesis and antimalarial activity of dldeoxyfebrifugine

dl-Deoxyfebrifugine (3) was synthesized from 2-piperidone (4) by two methods via the Wittig reaction of 2-hydroxypiperidine (6). The antimalarial activity of 3 was discussed.