249749-25-5Relevant academic research and scientific papers
Synthesis and cytotoxicity of ring C-Functionalized derivatives of the marine natural product (-)-dibromophakellstatin
Moldovan, Rares-Petru,Zoellinger, Michael,Jones, Peter G.,Kelter, Gerhard,Fiebig, Heinz-Herbert,Lindel, Thomas
experimental part, p. 685 - 698 (2012/03/27)
A structure-activity relationship study of ring C-functionalized derivatives of the cytotoxic marine natural product(-)-dibromophakellstatin from the sponge Phakellia mauritiana is reported. Functionalization of the pyrrolidine ring was achieved starting
Synthesis of a novel biotin-tagged photoaffinity probe for VEGF receptor tyrosine kinases
Han, Sun-Young,Park, Seok-Soon,Lee, Woo Ghil,Min, Yong Ki,Kim, Bum Tae
, p. 129 - 133 (2007/10/03)
A novel biotin-tagged photoaffinity probe was synthesized and evaluated as a vascular endothelial growth factor receptor-2 (VEGFR-2) tyrosine kinase inhibitor. The probe (2) is a potent VEGFR-2 inhibitor with an IC50 value of 7.1 μM, and inhibi
