25031-08-7 Usage
General Description
PIVALOYLOXYMETHYL 6-AMINOPENICILANATE, also known as pivampicillin, is a semisynthetic penicillin derivative that exhibits broad-spectrum antibiotic activity. It is an ester prodrug of ampicillin, an antibiotic that inhibits bacterial cell wall synthesis by binding to and inhibiting the action of penicillin-binding proteins. Pivampicillin is used in the treatment of various bacterial infections, including respiratory, urinary, and skin infections, among others. Upon oral administration, pivampicillin is rapidly hydrolyzed to release ampicillin, which then exerts its antibacterial effects. Pivampicillin is generally well-tolerated and is an effective treatment option for a range of bacterial infections.
Check Digit Verification of cas no
The CAS Registry Mumber 25031-08-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,0,3 and 1 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 25031-08:
(7*2)+(6*5)+(5*0)+(4*3)+(3*1)+(2*0)+(1*8)=67
67 % 10 = 7
So 25031-08-7 is a valid CAS Registry Number.
25031-08-7Relevant articles and documents
Synthesis of (Pivaloyloxy)methyl 6α-Fluoropenicillanate
Setti, Eduardo L.,Mascaretti, Oreste A.
, p. 2059 - 2060 (1988)
(Pivaloyloxy)methyl (Pom) 6α-fluoropenicillanate (2) was prepared in 15percent yield from the readily available (pyvaloyloxy)methyl 6-diazopenicillanate (1) and pyridinium poly(hydrogen fluoride).Its structure was established by 1H, 13C, and 19F n.m.r. spectroscopy and mass spectrometry.A new synthesis of Pom 6β-aminopenicillanate is described.
Acyloxymethyl esters of ampicillin.
Daehne,Frederiksen,Gundersen,Lund,Morch,Petersen,Roholt,Tybring,Godtfredsen
, p. 607 - 612 (2007/10/05)
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