250712-14-2Relevant academic research and scientific papers
Synthesis, physicochemical properties and biological evaluation of ester prodrugs of 3-hydroxypyridin-4-ones: Design of orally active chelators with clinical potential
Rai, Bijaya L.,Liu, Zu Dong,Liu, Ding Yong,Lu, Shu Li,Hider, Robert C.
, p. 475 - 485 (1999)
The synthesis of a range of hydrophobic ester prodrugs of 3- hydroxypyridin-4-ones with potential for oral administration is described. The distribution coefficient values of a range of these ester prodrugs and the corresponding alcohols in 1-octanol and
