2510-96-5

Basic information

• Product Name: α-phenylcinnamide
• Synonyms: α-phenylcinnamide
• CAS NO: 2510-96-5
• Molecular Weight: 223.274
• Mol File: 2510-96-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: α-phenylcinnamide(CAS DataBase Reference)
• NIST Chemistry Reference: α-phenylcinnamide(2510-96-5)
• EPA Substance Registry System: α-phenylcinnamide(2510-96-5)

Safety Data

• Hazardous Substances Data: 2510-96-5(Hazardous Substances Data)

Upstream product

• 140-29-4 phenylacetonitrile 
• 100-52-7 benzaldehyde 
• 501-65-5 diphenyl acetylene 
• 201230-82-2 carbon monoxide 
• 2510-95-4 2,3-diphenylacrylonitrile 

Downstream Products

• 451-40-1 phenyl benzyl ketone 
• 1202784-89-1 C₁₈H₁₅NO 

Relevant articles and documents

Nickel/Cobalt-Catalyzed Reductive Hydrocyanation of Alkynes with Formamide as the Cyano Source, Dehydrant, Reductant, and Solvent

A Ni/Co co-catalyzed reductive hydrocyanation of various alkynes was developed for the production of saturated nitriles. Hydrocyanic acid is generated in situ from safe and readily available formamide. Formamide played multiple roles as a cyano source, dehydrant, and reductant for the NiII pre-catalyst and vinyl nitriles, along with acting as the co-solvent in this reaction. Detailed mechanistic investigation supported a pathway via hydrocyanation of C≡C bond and the subsequent reduction of C=C bond. Wide substrate scope, the employment of a cheap and stable nickel salt as pre-catalyst, a safe cyano source and convenient experimental operation render this hydrocyanation practical for the laboratory synthesis of saturated nitriles. (Figure presented.).

An efficient InCl3-catalyzed hydration of nitriles to amides: acetaldoxime as an effective water surrogate

An efficient InCl3-catalyzed hydration protocol of nitriles to amides was developed. The reaction was carried out in toluene at refluxing temperature with the aid of acetaldoxime as an effective water surrogate to produce amides in high yields.