251099-27-1

Basic information

• Product Name: Silane, (1,1-dimethylethyl)[(2S)-2-[(4R,5S,6R)-6-[(1R)-2-iodo-1-methylethyl]-2, 2,5-trimethyl-1,3-dioxan-4-yl]propoxy]diphenyl-
• CAS NO: 251099-27-1
• Molecular Formula: C29H43IO3Si
• Molecular Weight: 594.649
• Mol File: 251099-27-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Silane, (1,1-dimethylethyl)[(2S)-2-[(4R,5S,6R)-6-[(1R)-2-iodo-1-methylethyl]-2, 2,5-trimethyl-1,3-dioxan-4-yl]propoxy]diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, (1,1-dimethylethyl)[(2S)-2-[(4R,5S,6R)-6-[(1R)-2-iodo-1-methylethyl]-2, 2,5-trimethyl-1,3-dioxan-4-yl]propoxy]diphenyl-(251099-27-1)
• EPA Substance Registry System: Silane, (1,1-dimethylethyl)[(2S)-2-[(4R,5S,6R)-6-[(1R)-2-iodo-1-methylethyl]-2, 2,5-trimethyl-1,3-dioxan-4-yl]propoxy]diphenyl-(251099-27-1)

Safety Data

• Hazardous Substances Data: 251099-27-1(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 97718-92-8 (S)-2-[(4R,5S,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-propan-1-ol 
• 106357-30-6 1-benzyloxy-2(S),4(S)-dimethyl-hex-5-en-3(R)-ol 
• 251099-25-9 (2S,3S,4R,5R,6S)-7-(tert-butyldiphenylsilyloxy)-3,5-(isopropylidenedioxy)-2,4,6-trimethyl-heptanol 
• 251099-23-7 methyl-(5S,6S,7R,8R,9S)-(E)-10-(tert-butyldiphenylsilyloxy)-6,8-(isopropylidenedioxy)-5,7,9-trimethyl-3-decenoate 
• 251099-21-5 methyl-(5S,6S,7R,8R,9S)-(E)-10-(tert-butyldiphenylsilyloxy)-6,8-dihydroxy-5,7,9-trimethyl-3-decenoate 
• 851889-69-5 (E)-(5S,6S,7R,8R,9S)-6,8,10-Trihydroxy-5,7,9-trimethyl-dec-3-enoic acid methyl ester 
• 184528-55-0 (3E,5R,6S,7S)-6,8-O-[bis-(1,1-dimethylethyl)silylene]-5,7-dimethylhex-3-enoic acid methyl ester 
• 184528-54-9 (3E,5R,6S,7S)-6,8-dihydroxy-5,7-dimethyloct-3-enoic acid methyl ester 
• 184758-35-8 (3E,5S,6S,7R,8R,9S)-(E)-8,10-O-[bis-(1,1-dimethylethyl)silylene]-6-hydroxy-5,7,9-trimethyldec-3-enoic acid methyl ester 
• 184528-56-1 (2S,3R,4S)-3,5-O-[bis-(1,1-dimethylethyl)silylene]-2,4-dimethylpropionaldehyde 
• 184528-51-6 (5R,6S,7S)-(E)-methyl-8-[(tert-butyldiphenylsilyl)oxy]-6-hydroxy-5,7-dimethyl-3-octenoate 
• 565226-27-9 4-[(1R,2S)-1-((S)-2-Benzyloxy-1-methyl-ethyl)-2-methyl-but-3-enyloxymethyl]-1,2-dimethoxy-benzene 
• 97689-63-9 (4S,5S,6R)-4-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-6-((S)-1-methyl-allyl)-[1,3]dioxane 

Downstream Products

• 251099-51-1 (2S,3R,4R,5S,6S,9S,10R,11S,12S,13R)-9-(tert-butyldimethylsiloxy)-11,13-((R)-benzylidenedioxy)-3,5-(isopropylidenedioxy)-8-methylene-2,4,6,10,12-pentamethyltetradecan-1-ol 
• 251099-50-0 (2R,3S,4S,5R,6S,9S,10S,11R,12R,13S)-6-(tert-butyldimethylsiloxy)-14-((tert-butyldiphenylsiloxy))-2,4-((R)-benzylidenedioxy)-10,12-(isopropylidenedioxy)-7-methylene-3,5,9,11,13-pentamethyltetradecane 
• 476622-79-4 (2R,3S,4R,5S,6S,9S,10R,11S,12S,13R)-9-(tert-butyldimethylsiloxy)-11-benzyloxy-13-hydroxy-3,5-(isopropylidenedioxy)-8-methylene-2,4,6,10,12-pentamethyltetradecan-1-al 
• 476622-81-8 (2R,3S,4R,5S,6S,9S,10R,11S,12R,13R)-9-(tert-butyldimethylsiloxy)-11-benzyloxy-3,5-(isopropylidenedioxy)-8-methylene-2,4,6,10,12,13-hexamethyltetradecanolide 
• 476622-78-3 (2S,3R,4R,5S,6S,9S,10R,11S,12S,13R)-9-(tert-butyldimethylsiloxy)-11-benzyloxy-3,5-(isopropylidenedioxy)-8-methylene-2,4,6,10,12-pentamethyltetradecan-1,13-diol 
• 476622-80-7 (2R,3S,4R,5S,6S,9S,10R,11S,12S,13R)-9-(tert-butyldimethylsiloxy)-11-benzyloxy-13-hydroxy-3,5-(isopropylidenedioxy)-8-methylene-2,4,6,10,12-pentamethyltetradecanoic acid 
• 476622-77-2 (2R,3S,4S,5R,6S,9S,10S,11R,12R,13S)-6-(tert-butyldimethylsiloxy)-14-((tert-butyldiphenylsiloxy))-2,4-((R)-benzylidenedioxy)-10,12-(isopropylidenedioxy)-3,5,9,11,13-pentamethyltetradecan-7-on 
• 565226-33-7 (S)-2-((4R,5R,6S)-6-{(S)-3-[(2S,4R,5R,6S)-6-[(1S,2R,3S,4S)-4-Benzyloxy-2-(4-methoxy-benzyloxy)-1,3-dimethyl-pentyl]-5-methyl-2-(2,4,6-trimethyl-phenyl)-[1,3]dioxan-4-yl]-1-methyl-but-3-enyl}-2,2,5-trimethyl-[1,3]dioxan-4-yl)-propan-1-ol 
• 565226-25-7 (R)-2-((4S,5R,6S)-6-{(S)-3-[(2S,4R,5R,6S)-6-((1S,2R,3R,4S)-4-Benzyloxy-2-hydroxy-1,3-dimethyl-pentyl)-5-methyl-2-(2,4,6-trimethyl-phenyl)-[1,3]dioxan-4-yl]-1-methyl-but-3-enyl}-2,2,5-trimethyl-[1,3]dioxan-4-yl)-propionic acid 
• 565226-37-1 C₄₂H₅₈O₉ 
• 565226-34-8 (1R,4S,5S,9S,10R,13R,14R,15S,17S,19R,20R)-13-((1S,2S)-2-Benzyloxy-1-methyl-propyl)-4,7,7,10,14,19,20-heptamethyl-2-methylene-17-(2,4,6-trimethyl-phenyl)-6,8,12,16,18-pentaoxa-tricyclo[13.3.1.1^5,9]icosan-11-one 
• 565226-36-0 C₄₀H₅₈O₈ 
• 1027918-84-8 (2S,5R,6R,7R,8R,9S,10S,11S)-11-Benzyloxy-2-[(4S,5R,6R)-6-((S)-2-hydroxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-9-(4-methoxy-benzyloxy)-6,8,10-trimethyl-4-methylene-dodecane-5,7-diol 

Relevant articles and documents

The first stereoselective total synthesis of lankanolide. Part 2

The seco-acid derivative designed by conformation calculation and lactonization experiment of model seco-acids was synthesized, and subjected to macrolactonization to afford the lactone derivative. The lankanolide was synthesized via several steps after the lactonization, and the synthetic lankanolide was confirmed to have the same physical data (NMR, mass, IR and αD) as the lankanolide prepared from lankamycin according to the reported method.

Total synthesis of oleandolide [6]

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