476622-80-7

Upstream product

• 476622-79-4 (2R,3S,4R,5S,6S,9S,10R,11S,12S,13R)-9-(tert-butyldimethylsiloxy)-11-benzyloxy-13-hydroxy-3,5-(isopropylidenedioxy)-8-methylene-2,4,6,10,12-pentamethyltetradecan-1-al 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 184528-64-1 (2S,3S)-3,4-(di(tert-butyldimethylsilyloxy))-2-methyl-butanal 
• 184528-51-6 (5R,6S,7S)-(E)-methyl-8-[(tert-butyldiphenylsilyl)oxy]-6-hydroxy-5,7-dimethyl-3-octenoate 
• 184528-56-1 (2S,3R,4S)-3,5-O-[bis-(1,1-dimethylethyl)silylene]-2,4-dimethylpropionaldehyde 
• 184758-35-8 (3E,5S,6S,7R,8R,9S)-(E)-8,10-O-[bis-(1,1-dimethylethyl)silylene]-6-hydroxy-5,7,9-trimethyldec-3-enoic acid methyl ester 
• 184528-54-9 (3E,5R,6S,7S)-6,8-dihydroxy-5,7-dimethyloct-3-enoic acid methyl ester 
• 184528-55-0 (3E,5R,6S,7S)-6,8-O-[bis-(1,1-dimethylethyl)silylene]-5,7-dimethylhex-3-enoic acid methyl ester 
• 851889-69-5 (E)-(5S,6S,7R,8R,9S)-6,8,10-Trihydroxy-5,7,9-trimethyl-dec-3-enoic acid methyl ester 
• 251099-45-3 (2S,3R,4S,5S,6R)-2-(tert-butyldimethylsilyloxy)-4,6-((R)-benzylidenedioxy)-3,5-dimethylheptanal 
• 251099-43-1 (2S,3R,4S,5S,6R)-2-(tert-butyldimethylsilyloxy)-4,6-((R)-benzylidenedioxy)-3,5-dimethylheptanol 
• 251099-47-5 (3S,4R,5S,6S,7R)-3-(tert-butyldimethylsilyloxy)-5,7-((R)-benzylidenedioxy)-4,6-dimethyloctan-2-one 
• 251099-32-8 methyl (5R,6S)-(E)-6,7-(di(tert-butyldimethylsilyloxy))-5-methyl-3-heptenoate 
• 251099-39-5 (2R,3S,4S,5R,6S)-6,7-(di(tert-butyldimethylsilyloxy))-3,5-dimethylheptane-2,4-diol 

Downstream Products

• 476622-81-8 (2R,3S,4R,5S,6S,9S,10R,11S,12R,13R)-9-(tert-butyldimethylsiloxy)-11-benzyloxy-3,5-(isopropylidenedioxy)-8-methylene-2,4,6,10,12,13-hexamethyltetradecanolide 

Relevant academic research and scientific papers

Asymmetric crotylation reactions in synthesis of polypropionate-derived macrolides: Application to total synthesis of oleandolide

Complete details of a convergent asymmetric synthesis of oleandolide (1), the aglycon of the macrolide antibiotic oleandomycin, is described. The synthesis has been achieved through the assembly and coupling of the left- and right-hand subunits 12 and 38,