25110-48-9Relevant academic research and scientific papers
Synthesis, antileishmanial activity and structure-activity relationship of 1-N-X-phenyl-3-N′-Y-phenyl-benzamidines
Rodrigues-Santos, Cláudio Eduardo,Leon, Leonor L.,Bortoluzzi, Adailton J.,Canto-Cavalheiro, Marilene Marcuzzo,Machado, Gérzia C.,Echevarria, Aurea
, p. 166 - 174 (2013/10/01)
Two series of N,N′-diphenyl-benzamidines were synthesized as part of a study to search potential new drugs with antileishmanial activity. These compounds were obtained by anilides in PCl5 halogenation reaction with generation in situ of the cor
A NOVEL DIRECT SYNTHESIS OF AMIDINES FROM CARBOXYLIC ACIDS AND AMINES USING POLYPHOSPHORIC ACID TRIMETHYLSILYL ESTER (PPSE) AS CONDENSING AGENT
Kakimoto, Masa-aki,Ogata, Shin-ichi,Mochizuki, Amane,Imai, Yoshio
, p. 821 - 824 (2007/10/02)
It was found that amidines were obtained directly by the reaction of carboxylic acids with amines in the presence of PPSE, and the yields of amidines were dependent on the structure of amines rather than that of carboxylic acids.
