25116-37-4

Basic information

• Product Name: 3-IODOBENZOPHENONE
• Synonyms: 3-IODOBENZOPHENONE;(3-IODOPHENYL)PHENYLMETHANONE
• CAS NO: 25116-37-4
• Molecular Formula: C₁₃H₉IO
• Molecular Weight: 308.11
• Mol File: 25116-37-4.mol

Chemical Properties

• Melting Point: 44 °C
• Boiling Point: 379.9°C at 760 mmHg
• Flash Point: 183.6°C
• Appearance: /
• Density: 1.624g/cm³
• Vapor Pressure: 5.67E-06mmHg at 25°C
• Refractive Index: 1.647
• CAS DataBase Reference: 3-IODOBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-IODOBENZOPHENONE(25116-37-4)
• EPA Substance Registry System: 3-IODOBENZOPHENONE(25116-37-4)

Safety Data

• Hazardous Substances Data: 25116-37-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H9IO/c14-12-8-4-7-11(9-12)13(15)10-5-2-1-3-6-10/h1-9H

Upstream product

• 1711-10-0 3-iodobenzoyl chloride 
• 71-43-2 benzene 
• 119-61-9 benzophenone 
• 2835-78-1 3-amino benzophenone 
• 90434-01-8 3-iodo-N-methylbenzamide 
• 100-58-3 phenylmagnesium bromide 
• 618-51-9 3-Iodobenzoic acid 
• 696-41-3 m-iodobenzaldehyde 
• 98-88-4 benzoyl chloride 

Downstream Products

• 91-01-0 1,1-Diphenylmethanol 
• 84359-23-9 (3-iodophenyl)(phenyl)methanol 
• 119-61-9 benzophenone 
• 1016-78-0 3-chlorobenzophenone 
• 1244029-39-7 C₃₃H₃₄O₅ 
• 1276111-31-9 (4-(phenylcarbonyl)phenyl)(mesityl)iodonium trifluoromethylsulfonate 
• 22161-81-5 S-ketoprofen 
• 13020-57-0 3-hydroxybenzophenone 
• 81601-93-6 (R)-(-)-2-(3-benzoylphenyl)propionic acid methyl ester 
• 1214274-01-7 C₁₃H₉⁽¹⁸⁾FO 
• 2835-78-1 3-amino benzophenone 
• 1169763-38-5 3-monoperfluorooctyl benzophenone 
• 75116-78-8 ethyl α-(3-benzoylphenyl)acrylate 
• 71953-00-9 (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)propionic acid tert-butyl ester 

Relevant articles and documents

Chemoselective Synthesis of Aryl Ketones from Amides and Grignard Reagents via C(O)-N Bond Cleavage under Catalyst-Free Conditions

Conversion of a wide range of N-Boc amides to aryl ketones was achieved with Grignard reagents via chemoselective C(O)-N bond cleavage. The reactions proceeded under catalyst-free conditions with different aryl, alkyl, and alkynyl Grignard reagents. α-Ketoamide was successfully converted to aryl diketones, while α,β-unsaturated amide underwent 1,4-addition followed by C(O)-N bond cleavage to provide diaryl propiophenones. N-Boc amides displayed higher reactivity than Weinreb amides with Grignard reagents. A broad substrate scope, excellent yields, and quick conversion are important features of this methodology.

Acyl hydrazides as acyl donors for the synthesis of diaryl and aryl alkyl ketones

In this communication we describe a novel strategy for the formation of valuable diaryl and aryl alkyl ketones from acyl hydrazides. A wide variety of ketones are prepared and the mild reaction conditions allow for the use of a range of functionalities, especially in the synthesis of diaryl ketones.

Enantioselective α-arylation of aldehydes via the productive merger of iodonium salts and organocatalysis

The enantioselective α-arylation of aldehydes has been accomplished using diaryliodonium salts and a combination of copper and organic catalysts. These mild catalytic conditions provide a new strategy for the enantioselective construction and retention of enolizable α-formyl benzylic stereocenters, a valuable synthon for the production of medicinal agents. As one example, this new asymmetric protocol has been applied to the rapid synthesis of (S)-ketoprofen, a commercially successful oral and topical analgesic.

Designed synthesis of multi-electrochromic systems bearing diaryl ketone and isophthalates

New multi-electrochromic systems have been developed through the combination of a diaryl ketyl radical system with isophthalate-based electrochromic materials. The location of the isophthalate group in compounds is very critical to obtaining different colors in the multi-electrochromism.

Synthesis and characterization of fullerene derivatives with perfluoroalkyl groups

Two novel C60 fullerene derivatives containing one or two perfluorooctyl groups were designed and efficiently synthesized. Organic field-effect transistors based on the bisperfluorooctyl compound 1 show high mobility up to 6.7 × 10-2 cm2 V-1 s and high on/off ratio up to 5 × 107, which qualifies compound 1 as promising n-type conductor material. The Royal Society of Chemistry 2009.

A one-pot method for the iodination of aryl amines via stable aryl diazonium silica sulfates under solvent-free conditions

A convenient and rapid one-pot method for the synthesis of iodoarenes is developed which involves the sequential diazotization-iodination of aromatic amines with sodium nitrite, silica sulfuric acid and potassium iodide under solvent-free conditions at room temperature. Various aromatic amines possessing electron-withdrawing groups or electron-donating groups are converted into the corresponding aryl iodides in good yields. Georg Thieme Verlag Stuttgart.

A catalyst-free synthesis of asymmetric diaryl ketones from aryltins

A series of diaryl ketones have been synthesized in good yields (40-78%) through the catalyst-free reaction of trimethylarylstannanes with aroyl chlorides in chlorobenzene as solvent. In addition, an attractive feature is that these reactions are completely regioselective making possible the synthesis of diarylketones which are not usually available under the influence of the directing forces of the substituents present in the aromatic ring. Also, the reaction conditions are mild enough to be applied to acid sensitive molecules.

Tetramethylammonium dichloroiodate: An efficient and environmentally friendly iodination reagent for iodination of aromatic compounds under mild and solvent-free conditions

Tetramethylammonium dichloroiodate (1, TMADCI) as a mild and efficient iodination reagent was prepared. Iodination of different aromatic compounds with this reagent takes place fast and with high yields under solvent-free conditions.