251353-52-3

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 91751-24-5 (R)-3-[(tert-butyldiphenylsilyl)oxy]-2-methylpropanal 
• 95514-03-7 (R)-methyl 3-(tert-butyl(diphenyl)silyloxy)-2-methylpropanoate 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 943253-13-2 C₂₂H₂₈O₂Si 
• 251353-66-9 (R)-3-(2-Trimethylsilanyl-ethoxycarbonyl)-pentanedioic acid (1S,3S,9R,10S,12S)-13-azido-9,10,12-tris-benzyloxy-1-((1R,2R)-1-benzyloxy-2-methyl-butyl)-3-methyl-tridec-5-ynyl ester 2-trimethylsilanyl-ethyl ester 
• 251353-67-0 (R)-3-Carboxy-pentanedioic acid mono-[(1S,3S,9R,10S,12S)-13-azido-9,10,12-tris-benzyloxy-1-((1R,2R)-1-benzyloxy-2-methyl-butyl)-3-methyl-tridec-5-ynyl] ester 
• 251353-62-5 Formic acid (6R,7S,9S)-6,7,9-tris-benzyloxy-1-((1R,3S,4R,5R)-4-benzyloxy-3-formyloxy-1,5-dimethyl-heptyl)-10-(tetrahydro-pyran-2-yloxy)-dec-2-ynyl ester 
• 251353-61-4 (3R,4R,5S,7R,13R,14S,16S)-4,13,14,16-Tetrakis-benzyloxy-5-hydroxy-3,7-dimethyl-17-(tetrahydro-pyran-2-yloxy)-heptadec-9-yn-8-one 
• 251353-72-7 (3R,4R,5S,7R,13R,14S,16S)-4,13,14,16-Tetrakis-benzyloxy-3,7-dimethyl-17-(tetrahydro-pyran-2-yloxy)-heptadec-9-yne-5,8-diol 
• 251353-73-8 (3R,4R,5S,7S,13R,14S,16S)-4,13,14,16-Tetrakis-benzyloxy-3,7-dimethyl-17-(tetrahydro-pyran-2-yloxy)-heptadec-9-yn-5-ol 
• 251353-63-6 Formic acid (1S,3S,9R,10S,12S)-9,10,12-tris-benzyloxy-1-((1R,2R)-1-benzyloxy-2-methyl-butyl)-3-methyl-13-(tetrahydro-pyran-2-yloxy)-tridec-5-ynyl ester 
• 251353-65-8 (3R,4R,5S,7S,13R,14S,16S)-17-Azido-4,13,14,16-tetrakis-benzyloxy-3,7-dimethyl-heptadec-9-yn-5-ol 
• 251353-64-7 (2S,4S,5R,11S,13S,14R,15R)-2,4,5,14-Tetrakis-benzyloxy-11,15-dimethyl-heptadec-8-yne-1,13-diol 
• 79367-52-5 AAL-toxin TA₁ 
• 251353-56-7 (4S,5R,6R)-5-Benzyloxy-7-(tert-butyl-diphenyl-silanyloxy)-1-ethoxy-6-methyl-hept-1-yn-4-ol 
• 251353-57-8 (S)-5-[(1R,2R)-1-Benzyloxy-3-(tert-butyl-diphenyl-silanyloxy)-2-methyl-propyl]-dihydro-furan-2-one 
• 251353-54-5 (2S,3R,4R)-3-Benzyloxy-5-(tert-butyl-diphenyl-silanyloxy)-4-methyl-pentane-1,2-diol 

Relevant academic research and scientific papers

A formal total synthesis of (+)-zincophorin. observation of an unusual urea-directed stork - Crabtree hydrogenation

A formal total synthesis of (+)-zincophorin via interception of Miyashita's advanced intermediates is described here. This effort features the first synthetic application of an inverse demand hetero [4 + 2] cycloaddition of a chiral allenamide, and the ob

Studies on a urea-directed Stork-Crabtree hydrogenation. Synthesis of the C1-C9 subunit of (+)-zincophorin

(Chemical Equation Presented) A detailed account on the stereoselective synthesis of the C1-C9 subunit of (+)-zincophorin is described here. This approach features the first application of a stereoselective inverse electron demand hetero-[4 + 2] cycloaddi

Total synthesis of AAL-toxin TA1

Two alternative synthetic routes of the left-half segment 5 have been developed. Efficient condensation between the left and right segments followed by Pd-catalyzed deoxygenation and further elaboration achieved the first total synthesis of AAL-toxin TAs