251453-08-4Relevant academic research and scientific papers
Synthesis of unsymmetrical biaryls from arylsilacyclobutanes
Denmark, Scott E.,Wu, Zhicai
, p. 1495 - 1498 (1999)
(formula presented) Aryl(fluoro)silacyclobutanes and aryl(chloro)silacyclobutanes have been found to undergo cross-coupling reactions with aryl iodides. The rate of reaction and extent of homocoupling were dramatically affected by the addition of ligands for the palladium catalyst. With (t-Bu)3P a wide range of electronically and structurally diverse unsymmetrical biaryls have been prepared in good to excellent yields.
