251453-07-3

Basic information

• Product Name: 1-(4-METHOXYPHENYL)-1-CHLOROSILACYCLOBUTANE
• Synonyms: 1-(4-METHOXYPHENYL)-1-CHLOROSILACYCLOBUTANE;1-(4-methoxyphenyl)-h-chlorosilacyclobutane
• CAS NO: 251453-07-3
• Molecular Formula: C₁₀H₁₃ClOSi
• Molecular Weight: 212.75
• Mol File: 251453-07-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 100°C/0/1mmHg
• Flash Point: 100.983°C
• Appearance: /
• Density: 1.119g/cm³
• Vapor Pressure: 0.008mmHg at 25°C
• Refractive Index: 1.528
• CAS DataBase Reference: 1-(4-METHOXYPHENYL)-1-CHLOROSILACYCLOBUTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-METHOXYPHENYL)-1-CHLOROSILACYCLOBUTANE(251453-07-3)
• EPA Substance Registry System: 1-(4-METHOXYPHENYL)-1-CHLOROSILACYCLOBUTANE(251453-07-3)

Safety Data

• TSCA: No
• Hazardous Substances Data: 251453-07-3(Hazardous Substances Data)

Usage

General Description

1-(4-Methoxyphenyl)-1-chlorosilacyclobutane is a chemical compound with the molecular formula C9H11ClOSi. It is a silacyclobutane derivative, which belongs to the class of organosilicon compounds. This chemical features a silicon atom bonded to a cyclobutane ring, with a chlorine atom and a 4-methoxyphenyl group attached to the silicon atom. 1-(4-Methoxyphenyl)-1-chlorosilacyclobutane has various potential applications in the field of organic synthesis and materials science due to the unique reactivity and physical properties of organosilicon compounds. It may also have uses in pharmaceutical research, electronics, and surface coatings.

InChI:InChI=1/C10H13ClOSi/c1-12-9-3-5-10(6-4-9)13(11)7-2-8-13/h3-6H,2,7-8H2,1H3

Upstream product

• 2351-33-9 1,1-dichlorosilacyclobutane 
• 13139-86-1 4-methoxyphenyl magnesium bromide 

Downstream Products

• 13021-18-6 1-(4'-methoxy-biphenyl-4-yl)-ethanone 
• 2143-90-0 4-methoxy-4'-nitrobiphenyl 
• 58743-77-4 4'-methoxybiphenyl-4-carbonitrile 
• 53040-92-9 4-(4-tolyl)anisole 
• 27331-33-5 1-(4-methoxyphenyl)naphthalene 
• 17171-17-4 4'-methoxy-3-methylbiphenyl 
• 251453-08-4 1-fluoro-1-(4'-methoxyphenyl)silacyclobutane 
• 20013-55-2 4'-methoxy-2-nitrobiphenyl 
• 5958-02-1 3-(4-methoxyphenyl)pyridine 
• 613-37-6 4-methoxylbiphenyl 
• 1379659-32-1 1-allyl-1-(4-methoxyphenyl)silacyclobutane 
• 57830-00-9 1-(4-methoxyphenyl)-1-methylsilacyclobutane 
• 1379659-40-1 C₁₅H₂₄O₃Si 
• 1379659-38-7 C₁₅H₂₀O₃Si 

Relevant articles and documents

Palladium-catalyzed desymmetrization of silacyclobutanes with alkynes: Enantioselective synthesis of silicon-stereogenic 1-sila-2-cyclohexenes and mechanistic considerations

A palladium-catalyzed enantioselective desymmetrization of silacyclobutanes with alkynes has been developed to give silicon-stereogenic 1-sila-2-cyclohexenes with high enantioselectivity. The products thus obtained undergo further derivatizations with complete stereoselectivity, and a new catalytic cycle involving alkyne coordination (oxidative cyclization)- transmetalation (σ-bond metathesis)-reductive elimination has also been proposed.

Synthesis of unsymmetrical biaryls from arylsilacyclobutanes

(formula presented) Aryl(fluoro)silacyclobutanes and aryl(chloro)silacyclobutanes have been found to undergo cross-coupling reactions with aryl iodides. The rate of reaction and extent of homocoupling were dramatically affected by the addition of ligands for the palladium catalyst. With (t-Bu)3P a wide range of electronically and structurally diverse unsymmetrical biaryls have been prepared in good to excellent yields.