2516-97-4Relevant articles and documents
Versatile synthesis of secondary 2-amino thiols and/or their disulfides via thiazolinium salts
Mercey, Guillaume,Lohier, Jean-Francois,Gaumont, Annie-Claude,Levillain, Jocelyne,Gulea, Mihaela
experimental part, p. 4357 - 4364 (2011/02/24)
Commercially available β-amino alcohols have been transformed into various secondary β-amino thiols and/or their disulfides by using methyl dithioacetate as a source of sulfur. The transformation involves a thiazolinium salt as a versatile key intermediate, which enables easy modulation of the product structure by varying the substituents on the hetero-cycle and the N-alkylating agent.