251998-53-5 Usage
Uses
Used in Pharmaceutical Industry:
(R)-4,5-ISOPROPYLIDENE-1-BROMOPENTANE is used as a building block for the synthesis of various pharmaceuticals. Its ability to undergo nucleophilic substitution and addition reactions makes it a versatile intermediate in the development of new drugs and medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, (R)-4,5-ISOPROPYLIDENE-1-BROMOPENTANE serves as a key intermediate in the production of agrochemicals. Its reactivity allows for the creation of compounds that can be used in the development of pesticides, herbicides, and other agricultural products.
Used in Fine Chemicals Industry:
(R)-4,5-ISOPROPYLIDENE-1-BROMOPENTANE is also utilized as an intermediate in the synthesis of fine chemicals. These chemicals are used in a wide range of applications, including the fragrance, flavor, and specialty chemical markets.
Safety and Handling:
Due to the reactivity and potential hazards associated with (R)-4,5-ISOPROPYLIDENE-1-BROMOPENTANE, it is crucial to handle and store (R)-4,5-ISOPROPYLIDENE-1-BROMOPENTANE with care. Adherence to proper safety guidelines is essential to minimize risks and ensure the safe use of this versatile intermediate in various chemical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 251998-53-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,1,9,9 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 251998-53:
(8*2)+(7*5)+(6*1)+(5*9)+(4*9)+(3*8)+(2*5)+(1*3)=175
175 % 10 = 5
So 251998-53-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H15BrO2/c1-8(2)10-6-7(11-8)4-3-5-9/h7H,3-6H2,1-2H3/t7-/m1/s1
251998-53-5Relevant articles and documents
Enantiomeric synthesis of the SPIKET-P enantiomers
Sharma, Anubha,Iyer, Prema,Gamre, Sunita,Chattopadhyay, Subrata
, p. 1037 - 1040 (2004)
A convenient synthesis of the antipodes of the title compound has been developed starting from (R)-1,2,5,6-dicyclohexylidene mannitol. Some of the key features of the syntheses were simple reaction protocols, and stereoselective inversion of chiral 1,2-diol moiety via neighbouring group assisted acetylation.
Total synthesis of a nonclassical bioactive acetogenin, (+)-muconin
Yang, Wen-Qian,Kitahara, Takeshi
, p. 1451 - 1461 (2007/10/03)
A convergent total synthesis of the tetrahydropyran-bearing acetogenin (+)-muconin 1 is described. All five chiral building blocks 7, 9, 17, 21, and 29 were prepared from D-glutamic acid, respectively. Four out of them were used to furnish the alkyne 16 and the iodoalkyne 33, respectively, and palladium(0)-mediated cross-coupling of alkynes 16 and 33, followed by hydrogenation, afforded 36. Simultaneous deprotection of the MOM and TBS groups in 36 with BF3·Et2O in the presence of Me2S provided (+)-muconin 1. (C) 2000 Elsevier Science Ltd.
Convergent synthesis of (+)-muconin
Yang, Wen-Qian,Kitahara, Takeshi
, p. 7827 - 7830 (2007/10/03)
An efficient total synthesis of the tetrahydropyran-bearing acetogenin muconin 1 is described. Palladium(0)-mediated crossed diyne coupling and the use of only D-glutamic acid as the origin of all absolute stereochemistry highlight this flexible approach that sets the stage for access to structural analogs for further study.
