251998-87-5Relevant articles and documents
Convergent synthesis of (+)-muconin
Yang, Wen-Qian,Kitahara, Takeshi
, p. 7827 - 7830 (1999)
An efficient total synthesis of the tetrahydropyran-bearing acetogenin muconin 1 is described. Palladium(0)-mediated crossed diyne coupling and the use of only D-glutamic acid as the origin of all absolute stereochemistry highlight this flexible approach that sets the stage for access to structural analogs for further study.