25220-31-9Relevant academic research and scientific papers
Synthesis and pharmacological evaluation of [(4-Arylpiperazin-1-yl)-alkyl]- carbamic acid ethyl ester derivatives as potential anxiolytic agents
Khatri, Manisha,Rai, Santosh K.,Ranbhor, Ranjit,Kishore, Krishna,Tiwari, Manisha
experimental part, p. 1143 - 1152 (2012/11/07)
On the basis of our earlier studies, a series of N-{4-[4-(aryl) piperazin-1-yl]-phenyl}-amine derivatives containing terminal carbamoyl fragment with alkyl spacer of different lengths (15-20) were synthesized as ligands, for 5-hydroxytryptamine-1A (5-HT1A
Further structure-activity relationships study of hybrid 7-{[2-(4-phenylpiperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2- ol analogues: identification of a high-affinity D3-preferring agonist with potent in vivo activity with long duration
Biswas, Swati,Zhang, Suhong,Fernandez, Fernando,Ghosh, Balaram,Zhen, Juan,Kuzhikandathil, Eldo,Reith, Maarten E. A.,Dutta, Aloke K.
, p. 101 - 117 (2008/09/20)
This paper describes an extended structure-activity relationships study of aminotetralin-piperazine-based hybrid molecules developed earlier for dopamine D2/D3 receptors. Various analogues as positional isomers have been developed where location of the ph
Synthesis of arylpiperazines with a terminal naphthothiazole group and their evaluation on 5-HT, DA and α receptors
Perrone,Berardi,Colabufo,Tortorella,Fornaretto,Caccia,McArthur
, p. 739 - 746 (2007/10/03)
The synthesis, affinities for 5-HT(1A), 5-HT2, D1, D2, α1 and α2 receptors and structure-activity relationships are described for a series of arylpiperazines substituted on the N-4 atom with an ω-(2-n
Anthelmintic 1-(substituted phenyl)-3-alkanimidoyl ureas
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, (2008/06/13)
The compounds of this invention are novel imidoylureas having anthelmintic activity and imidoylthioureas having antifertility activity. They are prepared by the reaction of appropriate amidines with appropriate isocyanates or isothiocyanates.
