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(2R,3S)-3-(FMOC-AMINO)-2-HYDROXY-3-PHENYL-PROPANOIC ACID, also known as N-Fmoc-(2R,3S)-3-phenylisoserine, is an N-Fmoc-protected form of (2R,3S)-3-phenylisoserine. It is an off-white powder that serves as a crucial reagent in the synthesis of Taxotere (D494422) and the Taxol side chain. (2R,3S)-3-(FMOC-AMINO)-2-HYDROXY-3-PHENYL-PROPANOIC ACID is significant in the pharmaceutical industry due to its role in the production of important chemotherapeutic agents.

252206-27-2

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252206-27-2 Usage

Uses

Used in Pharmaceutical Industry:
(2R,3S)-3-(FMOC-AMINO)-2-HYDROXY-3-PHENYL-PROPANOIC ACID is used as a reagent for the synthesis of Taxotere (D494422) and Taxol side chain. Its primary application is in the production of these chemotherapeutic drugs, which are vital in the treatment of various types of cancer.
Chemical Properties:
The compound is an off-white powder, which indicates its solid-state appearance and texture. This characteristic is essential for handling, storage, and processing during the synthesis of the targeted pharmaceutical compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 252206-27-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,2,2,0 and 6 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 252206-27:
(8*2)+(7*5)+(6*2)+(5*2)+(4*0)+(3*6)+(2*2)+(1*7)=102
102 % 10 = 2
So 252206-27-2 is a valid CAS Registry Number.

252206-27-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R,3S)-3-(FMOC-AMINO)-2-HYDROXY-3-PHENYL-PROPANOIC ACID

1.2 Other means of identification

Product number -
Other names (2R,3S)-3-(Fmoc-amino)-2-hydroxy-3-phenyl-propanoi

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:252206-27-2 SDS

252206-27-2Downstream Products

252206-27-2Relevant academic research and scientific papers

Preparation of α-hydroxy-β-Fmoc amino acids from N-Boc amino acids

Johnson, Erik P.,Hubieki, M. Patricia,Combs, Andrew P.,Teleha, Christopher A.

, p. 4023 - 4026 (2012/01/12)

A general method for the conversion of N-Boc amino acids into their homologated α-hydroxy-β-Fmoc amino acids is described. The protocol involved preparation of the amino aldehyde by reduction of the corresponding Weinreb amides, hydrocyanation, and hydrol

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