252206-27-2 Usage
Uses
Used in Pharmaceutical Industry:
(2R,3S)-3-(FMOC-AMINO)-2-HYDROXY-3-PHENYL-PROPANOIC ACID is used as a reagent for the synthesis of Taxotere (D494422) and Taxol side chain. Its primary application is in the production of these chemotherapeutic drugs, which are vital in the treatment of various types of cancer.
Chemical Properties:
The compound is an off-white powder, which indicates its solid-state appearance and texture. This characteristic is essential for handling, storage, and processing during the synthesis of the targeted pharmaceutical compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 252206-27-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,2,2,0 and 6 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 252206-27:
(8*2)+(7*5)+(6*2)+(5*2)+(4*0)+(3*6)+(2*2)+(1*7)=102
102 % 10 = 2
So 252206-27-2 is a valid CAS Registry Number.
252206-27-2Relevant academic research and scientific papers
Preparation of α-hydroxy-β-Fmoc amino acids from N-Boc amino acids
Johnson, Erik P.,Hubieki, M. Patricia,Combs, Andrew P.,Teleha, Christopher A.
, p. 4023 - 4026 (2012/01/12)
A general method for the conversion of N-Boc amino acids into their homologated α-hydroxy-β-Fmoc amino acids is described. The protocol involved preparation of the amino aldehyde by reduction of the corresponding Weinreb amides, hydrocyanation, and hydrol