819796-91-3

Basic information

• Product Name: Carbamic acid, [(1R)-2-(methoxymethylamino)-2-oxo-1-phenylethyl]-, 1,1-dimethylethyl ester
• CAS NO: 819796-91-3
• Molecular Formula: C15H22N2O4
• Molecular Weight: 294.351
• Mol File: 819796-91-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1R)-2-(methoxymethylamino)-2-oxo-1-phenylethyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1R)-2-(methoxymethylamino)-2-oxo-1-phenylethyl]-, 1,1-dimethylethyl ester(819796-91-3)
• EPA Substance Registry System: Carbamic acid, [(1R)-2-(methoxymethylamino)-2-oxo-1-phenylethyl]-, 1,1-dimethylethyl ester(819796-91-3)

Safety Data

• Hazardous Substances Data: 819796-91-3(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 33125-05-2 Boc-D-Phg-OH 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 

Downstream Products

• 137284-11-8 (2R)-2-N-(tert-butoxycarbonyl)amino-2-phenylethanal 
• 161453-08-3 C₉H₁₁NO₃*ClH 
• 1356606-76-2 (R)-3-(((9H-fluoren-9-yl)methoxy)carbonylamino)-2-hydroxy-3-phenylpropanoic acid 
• 1356606-53-5 (R)-tert-butyl 2-cyano-2-hydroxy-1-phenylethylcarbamate 
• 1192424-57-9 C₂₂H₃₁N₃O₂S 
• 1192424-55-7 C₂₂H₃₂N₂O₄S 
• 1192424-53-5 C₁₁H₁₃NO*ClH 
• 1192424-51-3 C₁₆H₂₁NO₃ 
• 819796-92-4 (R)-2-tert-butoxycarbonylamino-1,2-diphenylethanone 

Relevant articles and documents

COMPOUND HAVING NPY Y5 RECEPTOR ANTAGONIST ACTIVITY

This invention provides a compound of the formula (I): a pharmaceutically acceptable salt or solvate thereof, wherein R1 is substituted or unsubstituted alkyl or the like, R2 is hydrogen or substituted or unsubstituted alkyl, Ring A is monocyclic or bicyclic aromatic heterocycle, R3 is substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl or substituted or unsubstituted heterocycle, R4 is halogen, cyano, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl or the like, m is an integer between 0 and 2, n is an integer between 0 and 5, R is halogen, oxo, cyano, nitro, substituted or unsubstituted alkyl or the like, and p is an integer between 0 and 2 as novel compounds having NPY Y5 antagonistic activity.

Preparation of α-hydroxy-β-Fmoc amino acids from N-Boc amino acids

A general method for the conversion of N-Boc amino acids into their homologated α-hydroxy-β-Fmoc amino acids is described. The protocol involved preparation of the amino aldehyde by reduction of the corresponding Weinreb amides, hydrocyanation, and hydrol

Stille coupling of stereochemically defined α- sulfonamidoorganostannanes

Addition of tributylstannylmetallics to (R)-tert-butanesulfonimine derivatives of arylaldehydes provides α-sulfinamidostannanes with high (>98% de) diastereoselectivities. Oxidation of these compounds with m-CPBA gives α-sulfonamidostannanes which undergo Pd/Cu-catalyzed Stille-type couplings with benzoyl chloride. Best yields are achieved using the electron-rich tris(2,4,6-trimethoxyphenyl)phosphine as the ligand. Inversion of configuration at the benzylic carbon is observed. Copyright