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(4,5-Dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)phosphoramidic dichloride, also known as CID 24761759, is a chemical compound that serves as an intermediate in the synthesis of pharmaceuticals. It features a phosphoramidic dichloride group attached to a 4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl moiety, and is characterized as a colorless to yellow liquid with a molecular formula of C4H8Cl2N3O2P and a molecular weight of 220.994 g/mol. (4,5-Dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)phosphoramidic dichloride has the potential to participate in various chemical reactions and is commonly used as a precursor in the production of other organic compounds. Due to its potential hazards, including harmful effects if ingested, inhaled, or absorbed through the skin, and its ability to cause irritation to the eyes and skin, careful handling is advised.

25221-53-8

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25221-53-8 Usage

Uses

Used in Pharmaceutical Industry:
(4,5-Dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)phosphoramidic dichloride is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Organic Synthesis:
In the field of organic synthesis, (4,5-Dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)phosphoramidic dichloride is utilized as a precursor for the production of other organic compounds. Its reactivity and functional groups make it a valuable building block for creating a wide range of chemical entities, expanding the scope of synthetic chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 25221-53-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,2,2 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 25221-53:
(7*2)+(6*5)+(5*2)+(4*2)+(3*1)+(2*5)+(1*3)=78
78 % 10 = 8
So 25221-53-8 is a valid CAS Registry Number.

25221-53-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(dichlorophosphorylamino)-3-methyl-4H-imidazol-5-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:25221-53-8 SDS

25221-53-8Relevant academic research and scientific papers

Preparation method of myocardial protection medicine

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Paragraph 0024; 0033-0035; 0036-0038; 0039-0041; 0042-0044, (2021/07/01)

The invention discloses a preparation method of a myocardial protection medicine, belonging to the field of medicinal chemistry. The preparation method of the medicine comprises the following steps: carrying out a reflux reaction on creatinine and phosphorus oxychloride to prepare creatinine phosphoryl chloride, then subjecting the creatinine phosphoryl chloride to reacting with a sodium hydroxide solution to prepare a crude creatinine phosphate sodium product, and conducting refining to obtain a refined creatinine phosphate sodium product. According to the invention, product yield and quality are improved, reaction conditions in a preparation process are mild, production cost is low, a used solvent is safe and environment-friendly, and the method is suitable for industrial mass production.

A preparation method of creatinine

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Paragraph 0044; 0047; 0048, (2019/03/31)

The invention belongs to the technical field of chemical synthesis, in particular relates to a preparation method of creatinine, the method to creatine as the starting material, and containing 2 - 5 carbon of the lower saturated fatty acid reaction. The method of environmental protection, without by-product to produce, almost zero-emission, without refining can be directly used for cardiac muscle protective drug creatine phosphate sodium synthetic.

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