2524-05-2

Basic information

• Product Name: O,O-dipropyl chlorothiophosphate
• Synonyms: O,O-dipropyl chlorothiophosphate;Chloridothiophosphoric acid dipropyl ester;Phosphorochloridothioic acid O,O-dipropyl ester;DIPROPYL CHLOROTHIOPHOSPHATE;chloro-dipropoxy-sulfanylidene-$l^{5}-phosphane
• CAS NO: 2524-05-2
• Molecular Formula: C₆H₁₄ClO₂PS
• Molecular Weight: 216.665921
• EINECS: 219-757-5
• Mol File: 2524-05-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 241.6°Cat760mmHg
• Flash Point: 99.9°C
• Appearance: /
• Density: 1.179g/cm³
• Vapor Pressure: 0.0551mmHg at 25°C
• Refractive Index: 1.481
• CAS DataBase Reference: O,O-dipropyl chlorothiophosphate(CAS DataBase Reference)
• NIST Chemistry Reference: O,O-dipropyl chlorothiophosphate(2524-05-2)
• EPA Substance Registry System: O,O-dipropyl chlorothiophosphate(2524-05-2)

Safety Data

• Hazardous Substances Data: 2524-05-2(Hazardous Substances Data)

Usage

General Description

O,O-dipropyl chlorothiophosphate, also known as chlorpyrifos, is a highly toxic organophosphate pesticide used to control pests on a variety of crops. It is a cholinesterase inhibitor, meaning it disrupts the functioning of the nervous system by preventing the breakdown of the neurotransmitter acetylcholine. Exposure to O,O-dipropyl chlorothiophosphate can result in symptoms such as nausea, dizziness, headaches, and in severe cases, paralysis and respiratory failure. Long-term exposure has been linked to neurological and developmental disorders, especially in children. Due to its harmful effects on human health and the environment, the use of O,O-dipropyl chlorothiophosphate has been restricted in many countries.

InChI:InChI=1/C6H14ClO2PS/c1-3-5-8-10(7,11)9-6-4-2/h3-6H2,1-2H3

Upstream product

• 71-23-8 propan-1-ol 
• 2523-96-8 O-propyl thiophosphorodichloridate 
• 2272-08-4 O,O,O-tripropyl phosphorothioate 
• 14609-96-2 dipropyl thiophosphite 
• 64582-43-0 O,O-di-n-propyl-O-(2,5-dichloro-4-cyano-phenyl)-thionophosphate 
• 1809-21-8 di-n-propyl phosphonate 
• 5301-73-5 S-methyl O,O-dipropyl phosphorothioate 
• 2253-43-2 O_.O-Dipropyl-dithyophosphat 

Downstream Products

• 73077-18-6 phenyl-amidothiophosphoric acid O,O'-dipropyl ester 
• 51825-86-6 potassium O,O-dipropyl phosphorothioate 
• 900-24-3 Thiophosphorsaeure-diisopropylester-pentachlorphenylester 
• 138035-16-2 Thiophosphoric acid O,O'-dipropyl ester O''-[2,2,2-trichloro-1-(3-phenoxy-phenyl)-ethyl] ester 
• 138035-07-1 Thiophosphoric acid O-[cyano-(3-phenoxy-phenyl)-methyl] ester O',O''-dipropyl ester 
• 3244-90-4 aspon 
• 134202-28-1 [6-(Dipropoxy-thiophosphoryloxy)-5-methyl-5H-[1,2,4]triazin-4-yl]-phosphonothioic acid O,O-dipropyl ester 
• 135492-41-0 (5-Methyl-6-oxo-5,6-dihydro-1H-[1,2,4]triazin-4-yl)-phosphonothioic acid O,O-dipropyl ester 
• 135492-44-3 (5-Isopropyl-6-oxo-5,6-dihydro-1H-[1,2,4]triazin-4-yl)-phosphonothioic acid O,O-dipropyl ester 
• 3689-24-5 sulfotep 
• 134202-30-5 [6-(Dipropoxy-thiophosphoryloxy)-5-isopropyl-5H-[1,2,4]triazin-4-yl]-phosphonothioic acid O,O-dipropyl ester 
• 35812-35-2 (3-Methoxy-propyl)-thiophosphoramidic acid O,O'-dipropyl ester 
• 35812-42-1 (2-Methoxy-ethyl)-thiophosphoramidic acid O,O'-dipropyl ester 
• 35276-63-2 Thiophosphoric acid O-[(Z)-2-cyano-1-(4-methoxy-phenyl)-vinyl] ester O',O''-dipropyl ester 

Relevant articles and documents

Quinoline derivatives, and preparation method and use thereof

The invention belongs to the technical field of insecticides and acaricides, and particularly relates to quinoline derivatives, and a preparation method and a use thereof, and concretely provides compounds represented by formula (I), and stereoisomers, racemates, tautomers, isotope labels, oxynitrides, pharmaceutically acceptable salts or solvates thereof. The compounds of the formula (I) have an excellent activity against various pests and pest mites in the agricultural field or other fields. The compounds can achieve an excellent control effect at a very low dosage, so the compounds can be used to prepare insecticides and/or acaricides. In addition, the preparation steps of the compounds of the invention are simple, and the product yield is high, so that the compounds have a good application prospect.

Reaction of Thiolo and Selenolo Esters of Phosphorus Acids with Halogens. Part 3. Interaction of O,O,S-Trialkyl Phosphorothioates and O,S-Dialkyl t-Butylphosphonothioates with Sulphuryl Chloride and Halogens

The reaction of the title phosphono- and phosphoro-thiolates with sulphuryl chloride and halogens involves in every case the formation of intermediates containing two phosphorus atoms >P+(SR)OP(O)- (X = SO2Cl or halogen).The formation of the latter in the course of chlorinolysis of phosphorus thiolesters is suggested to be responsible for the occurrence of a mechanism involving retention of configuration.The effect of the structure of the reactants and the nature of solvent on the reaction stereochemistry is discussed.

ALCOHOLYSIS OF O-ALKYL PHOSPHORODICHLORIDOTHIOATES IN LOWER ALIPHATIC ALCOHOLS

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