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O,O-dipropyl chlorothiophosphate, commonly known as chlorpyrifos, is a highly toxic organophosphate pesticide that is utilized for controlling pests on a wide range of crops. It functions as a cholinesterase inhibitor, which means it interferes with the nervous system's operation by hindering the breakdown of the neurotransmitter acetylcholine. This pesticide is characterized by its significant potential to cause harm to both human health and the environment.

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  • 2524-05-2 Structure
  • Basic information

    1. Product Name: O,O-dipropyl chlorothiophosphate
    2. Synonyms: O,O-dipropyl chlorothiophosphate;Chloridothiophosphoric acid dipropyl ester;Phosphorochloridothioic acid O,O-dipropyl ester;DIPROPYL CHLOROTHIOPHOSPHATE;chloro-dipropoxy-sulfanylidene-$l^{5}-phosphane
    3. CAS NO:2524-05-2
    4. Molecular Formula: C6H14ClO2PS
    5. Molecular Weight: 216.665921
    6. EINECS: 219-757-5
    7. Product Categories: N/A
    8. Mol File: 2524-05-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 241.6°Cat760mmHg
    3. Flash Point: 99.9°C
    4. Appearance: /
    5. Density: 1.179g/cm3
    6. Vapor Pressure: 0.0551mmHg at 25°C
    7. Refractive Index: 1.481
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: O,O-dipropyl chlorothiophosphate(CAS DataBase Reference)
    11. NIST Chemistry Reference: O,O-dipropyl chlorothiophosphate(2524-05-2)
    12. EPA Substance Registry System: O,O-dipropyl chlorothiophosphate(2524-05-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 2524-05-2(Hazardous Substances Data)

2524-05-2 Usage

Uses

Used in Agricultural Industry:
O,O-dipropyl chlorothiophosphate is used as a pesticide for controlling a broad spectrum of pests in various agricultural settings. It is applied to protect crops from damage caused by insects, which can lead to increased yields and improved crop quality.
However, due to the associated health risks and environmental concerns, the use of O,O-dipropyl chlorothiophosphate has faced increasing restrictions in many countries. This has led to a push for the development of alternative, safer pest control methods that minimize the impact on human health and the environment.

Check Digit Verification of cas no

The CAS Registry Mumber 2524-05-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,2 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2524-05:
(6*2)+(5*5)+(4*2)+(3*4)+(2*0)+(1*5)=62
62 % 10 = 2
So 2524-05-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H14ClO2PS/c1-3-5-8-10(7,11)9-6-4-2/h3-6H2,1-2H3

2524-05-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name chloro-dipropoxy-sulfanylidene-λ<sup>5</sup>-phosphane

1.2 Other means of identification

Product number -
Other names dipropyl phosphorochloridothioate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2524-05-2 SDS

2524-05-2Relevant articles and documents

Quinoline derivatives, and preparation method and use thereof

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Paragraph 0182-0184, (2019/10/17)

The invention belongs to the technical field of insecticides and acaricides, and particularly relates to quinoline derivatives, and a preparation method and a use thereof, and concretely provides compounds represented by formula (I), and stereoisomers, racemates, tautomers, isotope labels, oxynitrides, pharmaceutically acceptable salts or solvates thereof. The compounds of the formula (I) have an excellent activity against various pests and pest mites in the agricultural field or other fields. The compounds can achieve an excellent control effect at a very low dosage, so the compounds can be used to prepare insecticides and/or acaricides. In addition, the preparation steps of the compounds of the invention are simple, and the product yield is high, so that the compounds have a good application prospect.

An efficient synthesis of O,O- di propyl (E)-2-[1-methyl 2-oxopropylidene]phosphorohydrazidothiolate (E) oxime and its analogues: A potential marine toxin

Gupta, Arvind K.,Dubey,Parashar,Kaushik

scheme or table, p. 1892 - 1910 (2009/08/07)

An efficient method for the synthesis of Ptychodiscus brevis toxin O,O- di n-propyl (E)-2-[1-methyl 2-oxopropylidene]phosphorohydrazidothiolate (E) oxime (TG-1) and its analogues has been developed using thermally stable and recyclable silica gel and Na2SO4 as a condensing agent and water scavenger, respectively. The compounds were evaluated against fish Rasbora daniconius by determining the LC50 and LC90 values. The results of biological evaluation showed that these compounds have high degree of toxicity. Copyright Taylor & Francis Group, LLC.

Reaction of Thiolo and Selenolo Esters of Phosphorus Acids with Halogens. Part 3. Interaction of O,O,S-Trialkyl Phosphorothioates and O,S-Dialkyl t-Butylphosphonothioates with Sulphuryl Chloride and Halogens

Krawiecka, Bozena,Wojna-Tadeusiak, Elzbieta

, p. 229 - 237 (2007/10/02)

The reaction of the title phosphono- and phosphoro-thiolates with sulphuryl chloride and halogens involves in every case the formation of intermediates containing two phosphorus atoms >P+(SR)OP(O)- (X = SO2Cl or halogen).The formation of the latter in the course of chlorinolysis of phosphorus thiolesters is suggested to be responsible for the occurrence of a mechanism involving retention of configuration.The effect of the structure of the reactants and the nature of solvent on the reaction stereochemistry is discussed.

2,5-Dichloro-4-cyano-phenyl esters of thionophosphoric, thionothiolphosphoric and thionophosphonic acids

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, (2008/06/13)

Compounds of the formula STR1 WHEREIN R1 is alkyl of 1 to 3 carbon atoms, and R2 is alkyl of 1 to 3 carbon atoms, phenyl, alkoxy of 1 to 3 carbon atoms or (alkyl of 1 to 4 carbon atoms)thio; The compounds are useful as insecticides, acaricides and fungicides.

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