25251-55-2

Basic information

• Product Name: (2-chloro-benzyl)-trimethyl-ammonium; bromide
• CAS NO: 25251-55-2
• Molecular Weight: 264.593
• Mol File: 25251-55-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-chloro-benzyl)-trimethyl-ammonium; bromide(CAS DataBase Reference)
• NIST Chemistry Reference: (2-chloro-benzyl)-trimethyl-ammonium; bromide(25251-55-2)
• EPA Substance Registry System: (2-chloro-benzyl)-trimethyl-ammonium; bromide(25251-55-2)

Safety Data

• Hazardous Substances Data: 25251-55-2(Hazardous Substances Data)

Upstream product

• 611-17-6 1-bromomethyl-2-chlorobenzene 
• 75-50-3 trimethylamine 
• 10175-31-2 1-(2-chlorophenyl)-N,N-dimethylmethanamine 

Relevant articles and documents

para-Selective C?H Borylation of Aromatic Quaternary Ammonium and Phosphonium Salts

Aromatic ammonium and phosphonium salts are important synthetic intermediates and multifunctional materials, but para-selective functionalization of the aromatic salts remains a challenge. Here we develop an ionic ligand based on our newly designed “biphenyl-phenanthroline” skeleton and realize the Ir-catalyzed para-selective C?H borylation of seven types of aromatic quaternary ammonium and phosphonium salts. Gram-scale transformation, late-stage elaboration for drug molecule, and diversification of borylated products demonstrate the potential utility of this reaction. The mechanistic studies and computational analysis elucidate the origin of para-selectivity.