25252-00-0

Usage

Chemical Properties

White powder

Upstream product

• 124-38-9 carbon dioxide 
• 589-87-7 1,4-bromoiodobenzene 
• 88-65-3 2-bromobenzoic-acid 

Downstream Products

• 762254-25-1 2-bromo-5-iodobenzoic acid benzyl ester 
• 865178-41-2 2-bromo-5-(2,2-dimethyl-propyl)benzylamine 
• 1261570-98-2 2-bromo-5-iodobenzoyl chloride 

Relevant academic research and scientific papers

Synthesis method of 2-halogen-5-iodobenzoic acid

The invention discloses a synthesis method of 2-halogen-5-iodobenzoic acid. The synthesis method comprises steps as follows: o-halogen benzoic acids are subjected to one-step iodo treatment in an iodio reagent, and 2-halogen-5-iodobenzoic acid is obtained. Aftertreatment comprises steps as follows: a reaction liquid is poured into a cold reductive water solution and quenched, a solvent is evaporated to dryness, recrystallization and filtration are performed, and a product can be obtained. The method is short in reaction route, simple to operate, environmentally friendly, safer and more economical and has broad application prospects.

Preparation method of 2-bromo-5-iodobenzyl alcohol

The invention discloses a preparation method of 2-bromo-5-iodobenzyl alcohol. A synthesis route is simple and typical, and is simple and convenient to operate, the yield of target products is high, 1,3-diiodo-5,5-dimethyl hydantoin as an iodization reagen

Synthesis of dilactone bridged terphenyls with crankshaft architectures

Three highly fluorescent dilactone bridged terphenyls with crankshaft architectures have been synthesized. This general class of compounds is relatively unexplored. These compounds have been characterized by fluorescence and UV-vis spectroscopy. For all three compounds, a direct correlation between the rigidity of the terphenyl system and the strength of absorption and emission of light has been observed. Preliminary studies have indicated that compounds with this architecture have the potential to be useful as pH-driven molecular switches and/or sensors with instant fluorescence attenuation at high pH values.

INHIBITORS OF STEAROYL-COA DESATURASE

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity.

Regioselective generation of aryllithiums from substituted bromobenzenes XC6H4Br (X = 4-Br, 4-I, 4-CN, 2-CN)

Selected activated bromobenzenes XC6H4Br (X = 4-Br, 4-I, 4-CN, 2-CN) were successfully deprotonated with lithium 2,2,6,6-tetramethylpiperidide (LTMP) in THF at -80°C. Thus, 2,5-dibromo-, 2-bromo-5-iodo-, 5-bromo-2-cyano-, and 3-bromo