252648-41-2Relevant articles and documents
One-Step Ruthenium-Catalysed Transformation of 1,7-Enynes into Strained Bicyclic Amino Esters
Moulin, Solenne,Roisnel, Thierry,Dérien, Sylvie
supporting information, p. 4311 - 4314 (2016/09/13)
The reaction of 1,7-enynes, synthesised from α-amino acids, carried out with diazo compounds in the presence of the Cp*RuCl(cod) catalyst allowed the one-step preparation of various strained bicyclic pipecolic acid derivatives in good yields under mild conditions. The stereoselectivity of the created double bond depends on the nature of the diazoalkane, and the diastereoselectivity arises essentially from steric factors.
Remote stereocontrol in reactions between 4- and 5-alkoxyalk-2- enylstannanes and 1-alkoxycarbonylimines and analogues: Stereoselective approaches to novel α-amino acids
Hallett, David J.,Tanikkul, Nongluk,Thomas, Eric J.
, p. 6130 - 6158 (2012/09/05)
Reactions of the allyltin trichloride 45 generated from (4S)-4-benzyloxypent-2-enyl(tributyl)stannane 1 with imines prepared from glyoxylates proceed with useful levels of 1,5-stereocontrol in favour of (4E)-2,6-anti-2-(alkylamino)-6-benzyloxyhept-4-enoat
Gold-catalyzed cycloisomerizations of ene-ynamides
Couty, Sylvain,Meyer, Christophe,Cossy, Janine
experimental part, p. 1809 - 1832 (2009/06/28)
The gold-catalyzed cycloisomerizations of 1,6-ene-ynamides proceed under mild conditions and lead to cyclobutanones from terminal or trimethylsilyl substituted ynamides, or to carbonyl compounds bearing a 2,3-methanopyrrolidine subunit from substrates pos
A Suzuki cross-coupling route to substituted aziridines
Lapinsky, David J,Bergmeier, Stephen C
, p. 8583 - 8586 (2007/10/03)
We have shown that the Suzuki cross-coupling reaction of olefinic aziridines is an effective route for the synthesis of substituted aziridines. This is the first example of a palladium coupling reaction applied to an aziridine-containing molecule. This method is complementary to other methods of aziridine synthesis utilizing organocuprate reagents.
Enantioselective synthesis of α,α'-disubstituted piperidines via ruthenium-catalyzed ring rearrangement
Voigtmann, Ulrike,Blechert, Siegfried
, p. 893 - 898 (2007/10/03)
A new method for the enantioselective synthesis of α,α'-disubstituted piperidines is described. Easily available cyclopentenones 5a,b rearrange via Ru-catalyzed RCM-ROM to heterocycles. Compound 6a is converted to the indolizidine 13.
Stereospecific synthesis of chiral N-(ethynyl)allylglycines and their use in highly stereoselective intramolecular Pauson-Khand reactions
Witulski, Bernhard,Goessmann, Matthias
, p. 1879 - 1880 (2007/10/03)
The first synthesis of an enantiopure N-ethynylated allylglycine and its application in the intramolecular Pauson-Khand reaction, which leads to a novel highly functionalised proline derivative with complete control of stereoselectivity, is reported.