252681-18-8 Usage
Description
(S)-3-Amino-2,2-difluoro-3-phenylpropionic acid HCl is a chemical compound that serves as an amino acid derivative with a unique structure featuring a fluorine substitution on the side chain and a phenyl group attached to the alpha carbon. (S)-3-Amino-2,2-difluoro-3-phenylpropionic acid HCl is in its hydrochloride salt form, which may contribute to its stability and solubility properties.
Uses
Used in Pharmaceutical Industry:
(S)-3-Amino-2,2-difluoro-3-phenylpropionic acid HCl is used as a building block for the synthesis of novel pharmaceuticals, particularly those targeting the central nervous system. Its unique structure and properties make it a promising candidate for the development of new drugs with improved pharmacological profiles.
Used in Organic Synthesis:
In the field of organic synthesis, (S)-3-Amino-2,2-difluoro-3-phenylpropionic acid HCl is used as a chiral building block. Its distinct structure allows for the creation of enantiomerically pure compounds, which are essential in the development of drugs with fewer side effects and higher efficacy.
Used in Drug Development:
(S)-3-Amino-2,2-difluoro-3-phenylpropionic acid HCl may also be utilized in drug development, where its unique properties can be leveraged to design and synthesize new drug molecules. Further research and development of this compound could lead to its incorporation into innovative pharmaceuticals with enhanced therapeutic benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 252681-18-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,2,6,8 and 1 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 252681-18:
(8*2)+(7*5)+(6*2)+(5*6)+(4*8)+(3*1)+(2*1)+(1*8)=138
138 % 10 = 8
So 252681-18-8 is a valid CAS Registry Number.
252681-18-8Relevant articles and documents
Enantioselective synthesis of α,α-difluoro-β-amino acid and 3,3- difluoroazetidin-2-one via the reformatsky-type reaction of ethyl bromodifluoroacetate with chiral 1,3-oxazolidines
Marcotte, Stephane,Pannecoucke, Xavier,Feasson, Christian,Quirion, Jean-Charles
, p. 8461 - 8464 (2007/10/03)
Chiral oxazolidines 2a-e can be diastereoselectively alkylated with BrCF2CO2Et to furnish 3,3-difluoroazetidin-2-ones 3a-e with up to 99% de. Selective cleavage of the chiral appendage provided the corresponding unsubstituted azetidinones. Formation of optically pure α,α-difluoro-β- amino acids 5a-c can be achieved by acidic hydrolysis of N-vinyl-azetidin-2- ones.
