252719-84-9

Upstream product

• 690267-73-3 acetic acid 2-(1-acetoxymethyl-2-phenyl-ethylamino)-9H-purin-6-yl ester 
• 252719-83-8 (2S)-2-[(6-chloro-9H-purin-2-yl)amino]-3-phenylpropyl acetate 
• 252719-81-6 2-(1-hydroxymethyl-2-phenyl-ethylamino)-9H-purin-6-ol 
• 87781-93-9 2-bromo-6-hydroxypurine 
• 3182-95-4 L-Phenylalaninol 
• 690267-69-7 (2S)-2-[(6-chloro-9H-purin-2-yl)amino]-3-phenyl-1-propanol 

Downstream Products

• 252719-85-0 (2R,3R,4R,5R)-2-(6-amino-2-{[(1S)-2-hydroxy-1-(phenylmethyl)ethyl]amino}-9H-purin-9-yl)-5-(2-ethyl-2H-tetrazol-5-yl)tetrahydrofuran-3,4-diyl diacetate 

Relevant academic research and scientific papers

Efficient Synthesis of an Adenosine A2a Agonist: Glycosylation of 2-Haloadenines and an N2-Alkyl-6-chloroguanine

A convergent synthesis of adenosine A2a agonist 1 in the form of its maleate salt 2 was achieved. The key step in this approach was the highly selective 9β-glycosylation reaction between 2-haloadenines or an N 2-alkyl-6-chloroguanine and a D-ri

2-(Purin -9-yl)-tetrahydrofuran-3,4-diol derivatives

A series of 2-(Purin-9-yl)-tetrahydrofuran-3,4-diol derivatives with broad anti-inflammatory properties which inhibit leukocyte recruitment and activation and which are agonists of the adenosine 2areceptor are described.