690267-73-3

Upstream product

• 108-24-7 acetic anhydride 
• 252719-81-6 2-(1-hydroxymethyl-2-phenyl-ethylamino)-9H-purin-6-ol 
• 3182-95-4 L-Phenylalaninol 
• 87781-93-9 2-bromo-6-hydroxypurine 

Downstream Products

• 252719-83-8 (2S)-2-[(6-chloro-9H-purin-2-yl)amino]-3-phenylpropyl acetate 
• 252719-85-0 (2R,3R,4R,5R)-2-(6-amino-2-{[(1S)-2-hydroxy-1-(phenylmethyl)ethyl]amino}-9H-purin-9-yl)-5-(2-ethyl-2H-tetrazol-5-yl)tetrahydrofuran-3,4-diyl diacetate 
• 690267-70-0 (2R,3R,4R,5R)-2-(6-chloro-2-{[(1S)-2-hydroxy-1-(phenylmethyl)ethyl]amino}-9H-purin-9-yl)-5-(2-ethyl-2H-tetrazol-5-yl)tetrahydrofuran-3,4-diyl diacetate 
• 252719-84-9 (2S)-2-[(6-amino-9H-purin-2-yl)amino]-3-phenyl-1-propanol 
• 690267-69-7 (2S)-2-[(6-chloro-9H-purin-2-yl)amino]-3-phenyl-1-propanol 

Relevant academic research and scientific papers

Efficient Synthesis of an Adenosine A2a Agonist: Glycosylation of 2-Haloadenines and an N2-Alkyl-6-chloroguanine

A convergent synthesis of adenosine A2a agonist 1 in the form of its maleate salt 2 was achieved. The key step in this approach was the highly selective 9β-glycosylation reaction between 2-haloadenines or an N 2-alkyl-6-chloroguanine and a D-ri