252882-62-5

Basic information

• Product Name: Benzonitrile, 4-[[2,3-dihydro-5-(hydroxymethyl)-2-thioxo-1H-imidazol-1-yl]methyl]-
• CAS NO: 252882-62-5
• Molecular Formula: C12H11N3OS
• Molecular Weight: 245.305
• Mol File: 252882-62-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 4-[[2,3-dihydro-5-(hydroxymethyl)-2-thioxo-1H-imidazol-1-yl]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4-[[2,3-dihydro-5-(hydroxymethyl)-2-thioxo-1H-imidazol-1-yl]methyl]-(252882-62-5)
• EPA Substance Registry System: Benzonitrile, 4-[[2,3-dihydro-5-(hydroxymethyl)-2-thioxo-1H-imidazol-1-yl]methyl]-(252882-62-5)

Safety Data

• Hazardous Substances Data: 252882-62-5(Hazardous Substances Data)

Upstream product

• 96-26-4 dihydroxyacetone 
• 333-20-0 potassium thioacyanate 
• 17201-43-3 4-cyanobenzyl bromide 
• 62147-49-3 1,3-dihydroxyacetone dimer 

Downstream Products

• 183500-36-9 4-(5-hydroxymethyl-imidazol-1-ylmethyl)-benzonitrile 

Relevant articles and documents

Method of treating cancer

The present invention relates to methods of treating cancer using a combination of a compound which is a PSA conjugate and a compound which is a inhibitor of prenyl-protein transferase, which methods comprise administering to said mammal, either sequentially in any order or simultaneously, amounts of at least two therapeutic agents selected from a group consisting of a compound which is a PSA conjugate and a compound which is a inhibitor of prenyl-protein transferase. The invention also relates to methods of preparing such compositions.

INHIBITORS OF PRENYL-PROTEIN TRANSFERASE

The present invention comprises piperazine/piperazinone-containing compounds having multicyclic ring system substituents on one of the piperazine/piperazinone nitrogens, which inhibit prenyl-protein transferases, including farnesyl-protein transferase and geranylgeranyl-protein transferase type I. Such therapeutic compounds are useful in the treatment of cancer

Sustained release drug dispersion delivery device

The present invention is related to a drug delivery device, that is pH insensitive, for the sustained in situ production and release of a dispersion, in an environment of use, which comprises a) a compressed core prepared from an admixture comprising i) a