25308-58-1Relevant academic research and scientific papers
Synthesis, DNA-damaging and cytotoxic properties of novel topoisomerase II-directed bisantrene analogues
Zagotto, Giuseppe,Oliva, Ambrogio,Guano, Fulvio,Menta, Ernesto,Capranico, Giovanni,Palumbo, Manlio
, p. 121 - 126 (1998)
New bisantrene analogues were synthesized, bearing one or two 4,5-dihydro-1H-imidazol-2-yl hydrazone side chains at positions 1,4 or 9 of the anthracene ring system. A 10-aza-bioisostere was also prepared. The position of substituents in structurally isomeric drugs modulates topoisomerase II poisoning and specificity, along with cytotoxicity.
Tunable chiral reaction media based on two-component liquid crystals: Regio-, diastereo-, and enantiocontrolled photodimerization of anthracenecarboxylic acids
Ishida, Yasuhiro,Achalkumar, Ammathnadu S.,Kato, Shun-Ya,Kai, Yukiko,Misawa, Aya,Hayashi, Yumi,Yamada, Kuniyo,Matsuoka, Yuki,Shiro, Motoo,Saigo, Kazuhiko
supporting information; experimental part, p. 17435 - 17446 (2011/02/27)
Three kinds of enantiopure amphiphilic amino alcohols (1a-c) were newly synthesized, of which the stereochemistry of the stereogenic carbons adjacent to the amino (C2) and hydroxy (C1) groups was systematically varied. By using these amino alcohols and fo
Photoisomerization and Photocyclization Reactions of 1-Styrylanthracene
Karatsu, Takashi,Kitamura, Akihide,Zeng, Hualing,Arai, Tatsuo,Sakuragi, Hirochika,Tokumaru, Katsumi
, p. 920 - 928 (2007/10/02)
On triplet sensitization, 1-styrylanthracene (1SA) undergoes adiabatic cis->trans one-way isomerization (3c*->3t*) similarly to 2-anthrylethylenes.However, upon direct irradiation, cis-1SA in the singlet excited state mostly undergoes cyclization to a dihydrophenanthrene-type product (DHP), 4a,4b-dihydrobenzochrysene, competing with an inefficient intersystem crossing to 3c* followed by one-way isomerization.The produced DHP, in deaerated benzene, is reverted to cis-1SA by a thermal (Ea = 14.9 kcal mol-1) or a photochemical pathway; however, under an oxygenated atmosphere DHP gives benzochrysene.A failure in the production of a cyclized product upon the excitation of trans-1SA shows that the isomerization really takes place in a one-way fashion.
