3752-42-9Relevant academic research and scientific papers
1 - [...] synthetic preparation method
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, (2019/02/13)
The invention discloses a 1 - [...] synthetic preparation method, comprises the following steps: S1) will anthracene and acetyl chloride is dissolved in the solvent, and the catalysis of a Lewis acid, reaction to obtain the 1 - b [...]; S2) 1 - b [...] through oxidation reaction, to obtain 1 - carboxylic acid anthracene; S3) under the action of the acyl, firstly the 1 - anthracene acid radical chloride acid, to remove the surplus solvent, followed by reaction with cyanide, to produce the target compound 1 - cyanate anthracene. The present invention provides 1 - [...] synthetic preparation method, in order to low-cost transfer catalyst, acetyl chloride as the raw material, after three step synthesis of simple and convenient operation, and then after treatment and purification, can prepare and get the purity 98% or more of 1 - [...], not only the production cost is low, the experimental steps are few, simple operation, and after the simple purification, the purity can reach 98% above, can fully meet the T - 2 toxin of the derivatization detection, greatly reduce the T - 2 toxin detection cost.
A mild and efficient palladium-catalyzed cyanation of aryl chlorides with K4[Fe(CN)6]
Yeung, Pui Yee,So, Chau Ming,Lau, Chak Po,Kwong, Fuk Yee
supporting information; experimental part, p. 648 - 651 (2011/04/15)
An efficient palladium-catalyzed cyanation of aryl chlorides is established. In the presence of a highly effective Pd/CM-phos catalyst, cyanation of aryl chlorides proceeds at 70 °C in general, which is the mildest reaction temperature achieved so far for this process. Common functional groups such as keto, aldehyde, ester, nitrile and-NH2, and heterocyclic coupling partners including N-H indoles are well tolerated. Moreover, a sterically hindered nonactivated ortho,ortho-disubstituted electrophile is shown to be a feasible coupling partner in cyanation.
Tetrachloropyridine: A new reagent for the dehydration of aldoximes under microwave
Lingaiah, Nagarapu,Narender, Ravirala
, p. 2391 - 2394 (2007/10/03)
Dehydration of aldoximes to nitriles using tetrachloropyridine under microwave in dry media is described. The procedure is applicable to a variety of aldoximes and the reagent can be recycled and reused.
Efficient One-Pot Preparation of Nitriles from Aldehydes using N-Methyl-pyrrolidone
Kumar, H. M. Sampath,Reddy, B. V. Subba,Reddy, P. Tirupathi,Yadav, J. S.
, p. 586 - 587 (2007/10/03)
Various aromatic and aliphatic nitriles were prepared in high yields in a direct one-pot process by heating corresponding aldehydes with hydroxylamine hydrochloride in N-methylpyrrolidone at 110-115 deg C. - Keywords: aldehyde; oxime; N-methylpyrrolidone; nitrile
Dehydration of aldoximes to nitriles with clay
Meshram
, p. 943 - 944 (2007/10/02)
The dehydration of alkyl, aryl, heterocyclic and polynuclear aldehyde oximes with montmorillonite KSF as catalyst is reported.
