253189-23-0

Upstream product

• 253189-35-4 (R)-3-tert-Butoxycarbonylamino-3-{5-[(5R,6R,7S)-6-(tert-butyl-dimethyl-silanyloxy)-9-iodo-2,2-dimethyl-1,3-dioxa-spiro[4.4]non-8-en-7-yloxy]-6-chloro-pyridin-2-yl}-propionic acid methyl ester 
• 253189-34-3 (R)-3-tert-Butoxycarbonylamino-3-{5-[(1S,4R,5R)-5-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-4-hydroxymethyl-3-iodo-cyclopent-2-enyloxy]-6-chloro-pyridin-2-yl}-propionic acid methyl ester 
• 253189-30-9 Acetic acid (1R,2R,5S)-2-acetoxymethyl-5-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-3-iodo-cyclopent-3-enyl ester 
• 253189-28-5 Acetic acid (1R,4S,5R)-1-acetoxymethyl-2-iodo-4,5-bis-methoxymethoxy-cyclopent-2-enyl ester 
• 253189-17-2 Acetic acid (1R,2R,5S)-2-acetoxymethyl-2,5-dihydroxy-3-iodo-cyclopent-3-enyl ester 
• 253189-16-1 (1R,4S,5R)-1-Hydroxymethyl-2-iodo-4,5-bis-methoxymethoxy-cyclopent-2-enol 
• 253189-15-0 (3S,6S,7R)-4-Iodo-6,7-bis-methoxymethoxy-1-oxa-spiro[2.4]hept-4-ene 
• 253189-14-9 (4S,5R)-2-Iodo-4,5-bis-methoxymethoxy-cyclopent-2-enone 
• 253189-21-8 (R)-3-tert-Butoxycarbonylamino-3-{5-[(5R,6R,7S)-6-(tert-butyl-dimethyl-silanyloxy)-9-iodo-2,2-dimethyl-1,3-dioxa-spiro[4.4]non-8-en-7-yloxy]-6-chloro-pyridin-2-yl}-propionic acid 

Downstream Products

• 253189-24-1 C₅₇H₈₈ClIN₂O₁₂Si₃ 
• 253189-26-3 C₅₇H₈₇ClN₂O₁₂Si₃ 

Relevant academic research and scientific papers

Synthetic study of kedarcidin chromophore: Atropselective construction of the ansamacrolide

The ansamacrolide moiety of kedarcidin has been constructed with complete atropselectivity via intramolecular Sonogashira coupling.

Synthesis of the entire carbon framework of the kedarcidin chromophore aglycon

In advanced studies directed toward the total synthesis of the kedarcidin chromophore, we have successfully achieved the late-stage installation of the nine-membered diyne ring in the presence of the highly functionalised ansamacrocyclic bridge. The Royal