25323-58-4Relevant articles and documents
Novel pyrrolopyridine derivatives and its use as HIV inhibitor
-
, (2018/03/09)
The present invention relates to a pyrrolopyridine derivative expressed as chemical formula 1, specifically a compound including a substituent group having an oxatane group in R1, its stereoisomer or racemic body, their pharmaceutically acceptable salts or their solvate, a manufacturing method thereof, and an antivirus composition containing the same as an active ingredient, wherein the compound expressed as chemical formula 1 has excellent selectivity and physiological activity with respect to wild type or resistant HIV-1 and therefore can be used as a remedy for AIDS.
Synthesis and properties of poly
Ameduri, Bruno,Boutevin, Bernard,Karam, Lina
, p. 43 - 48 (2007/10/02)
The synthesis of poly has been performed in four steps.Chlorination of pentaerythritol produced a mixture of halogenated alcohols, which, in an alkaline medium, led to a mixture of hydroxylated and chlorinated oxetanes.Of these, the bis(3-chloromethyl) oxetane (BCMO) was etherified with C6F13C2H4OH via phase-transfer catalysis to yield the mono- and di-substituted fluorinated oxetanes.In a last step, the mono-substituted oxetane was cationically polymerized using BF3*OEt2 as the catalyst, and was characterized by 1H and 13C NMR spectroscopy.Finally, several physical properties have been determined such as the viscosity, glass transition and decomposition temperatures, and surface properties.