25354-72-7

Basic information

• Product Name: 1,3-Butanedione, 1-phenyl-2-(phenylmethylene)-
• CAS NO: 25354-72-7
• Molecular Formula: C17H14O2
• Molecular Weight: 250.297
• Mol File: 25354-72-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,3-Butanedione, 1-phenyl-2-(phenylmethylene)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Butanedione, 1-phenyl-2-(phenylmethylene)-(25354-72-7)
• EPA Substance Registry System: 1,3-Butanedione, 1-phenyl-2-(phenylmethylene)-(25354-72-7)

Safety Data

• Hazardous Substances Data: 25354-72-7(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 93-91-4 1-phenylbutan-1,3-dione 

Downstream Products

• 137451-61-7 5-acetyl-4,6-diphenyl-2-thioxo-1,2-dihydro-pyridine-3-carbonitrile 
• 1380077-12-2 (R)-2-amino-5-benzoyl-6-methyl-4-phenyl-4H-pyran-3-carbonitrile 
• 101413-30-3 1-(5'-phenyl-[1,1':3',1''-terphenyl]-2'-yl)ethanone 
• 28918-08-3 2-benzyl-1-phenylbutane-1,3-dione 
• 2550-26-7 4-Phenyl-2-butanone 
• 127382-06-3 5-benzoyl-1,2-dihydro-6-methyl-4-phenyl-3H-pyrazolo<3,4-b>pyridin-3-one 
• 4974-44-1 N'-benzylidene-2-cyanoacetohydrazide 
• 96384-64-4 2-phenyl-1,3-diacetyl-1,3-dibenzoylpropane 
• 39566-40-0 (2-methyl-4-phenyl-4,5-dihydrofuran-3-yl)(phenyl)methanone 
• 39568-09-7 1-(2,4-diphenyl-4,5-dihydrofuran-3-yl)ethanone 
• 139884-16-5 5-Acetyl-4,6-diphenyl-2-pyrrolidin-1-yl-4H-pyran-3-carboxylic acid methyl ester 

Relevant articles and documents

Minute synthesis of electrophilic alkenes under microwave irradiation

Condensation of carbonyl derivatives 2 with active methylene compounds 1 is efficiently achieved, within 3 to 15 minutes under microwave irradiation by a solvent free reaction in the presence of carefully adjusted amounts of piperidine leading to Knocvenagel products 3 in good to excellent yields.

Construction of Multi-Substituted Benzenes via NHC-Catalyzed Reactions of Carboxylic Esters

A carbene-catalyzed ester activation reaction for the synthesis of multi-substituted benzenes is developed. Tetra-substituted benzene compounds are efficiently synthesized through this methodology. Compared with aldehyde substrates used in previous reports, the ester substrates used here are much more readily available and inexpensive. In addition, the TEMPO oxidant used here is more inexpensive than the quinones commonly used in related carbene-catalyzed reactions.

The Complex Reaction of Acetohydrazides with Unsaturated Diketones: Alternative Cyclizations to 1,2-Diazepin-3-ones and Pyrazolopyridines

The reaction of 2-cyanoacetohydrazide (1) and 2-(ethoxycarbonyl)acetohydrazide (26) with unsaturated 1,3-diketones leading with moderate yields to 1,2-diazepinones (3, 23, 24) and pyrazolopyridines (5, 15, 20, 25) together with the corresponding acetohydrazones have been studied.The reaction course depends on the temperature and the relative reactivity of the carbonyl groups of the starting materials.When one of these carbonyl groups is less reactive (benzoyl or ethoxycarbonyl groups), the reaction does not yield diazepinones but only pyrazolopyridines and/or acetohydrazones.