25364-47-0Relevant articles and documents
A magnetically separable palladium catalyst containing a bulky N-heterocyclic carbene ligand for the Suzuki-Miyaura reaction
Wang,Yu,Zhang,Li,Qian,Lin
, p. 413 - 420 (2015)
This work describes the preparation and characterization of a magnetic palladium catalyst with bulky N-heterocyclic carbene (NHC) ligands for the Suzuki-Miyaura cross-coupling reaction. After the 1-(2,6-diisopropylphenyl)-1H-imidazole (1-arylimidazole) was modified on the surface of magnetic polymer carriers, palladium diacetate was employed to synthesize the Pd-NHC complex, affording a palladium loading of 0.23 mmol g?1. This magnetic catalyst showed high catalytic activity towards the Suzuki-Miyaura reaction of phenylboronic acids with aryl bromides in the ethanol-water solution (TON > 87 000). After 21 cycling runs, its catalytic activity decreased slightly, and no leaking of palladium was found either in products or in reaction residue. When other sources of palladium (PdCl2 and 3-Cl-pyridi-nyl) were employed to synthesize the palladium complex, the stability of the magnetic catalyst was greatly improved to perform the catalysis of Suzuki-Miyaura reactions with aryl chlorides at 100 °C.
Novel N-heterocyclic carbene cyclic palladium compound as well as preparation method and application thereof
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Paragraph 0027-0029; 0034, (2021/06/26)
The invention discloses a novel N-heterocyclic carbene cyclic palladium compound as well as a preparation method and application thereof, and belongs to the technical field of organic catalysis. The novel N-heterocyclic carbene cyclic palladium compound is prepared by the following steps: heating, stirring and mixing N-(4-butoxybenzyl)-N-ethylethylamine, palladium chloride and an organic solvent in an inert gas atmosphere, then adding potassium carbonate, performing stirring and mixing, and finally adding 1-(2,6-diisopropyl phenyl)-3-butyl-brominated imidazole for reflux reaction; and after the reaction is finished, performing quenching with an acid solution, performing extracting to obtain a crude product, and performing column chromatography separation and purification to obtain the novel N-heterocyclic carbene cyclic palladium compound. The N-heterocyclic carbene cyclic palladium compound provided by the invention has high catalytic activity, can catalyze cross-coupling reactions between aryl chloride and aryl phenylboronic acid and between aryl chloride and secondary amine in a catalytic amount of 1 mol%, and can be used as a high-efficiency catalyst for the coupling reactions.
NHC copper complexes functionalized with sulfoxide and sulfone moieties
Szadkowska, Anna,Paw?owski, Robert,Zaorska, Ewelina,Staszko, Sebastian,Trzybiński, Damian,Wo?niak, Krzysztof
, (2019/05/21)
A series of N-heterocyclic copper carbene complexes bearing sulfoxide and sulfone moieties have been prepared. In case of new copper compounds with sulfone ligand, the solid-state structures were determined using X-Ray crystallography. Obtained complexes