950677-69-7

Basic information

• Product Name: 1-(2,2-diethoxy-ethyl)-3-(2,6-diisopropyl-phenyl)-thiourea
• Synonyms: 1-(2,2-diethoxy-ethyl)-3-(2,6-diisopropyl-phenyl)-thiourea
• CAS NO: 950677-69-7
• Molecular Weight: 352.541
• Mol File: 950677-69-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(2,2-diethoxy-ethyl)-3-(2,6-diisopropyl-phenyl)-thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,2-diethoxy-ethyl)-3-(2,6-diisopropyl-phenyl)-thiourea(950677-69-7)
• EPA Substance Registry System: 1-(2,2-diethoxy-ethyl)-3-(2,6-diisopropyl-phenyl)-thiourea(950677-69-7)

Safety Data

• Hazardous Substances Data: 950677-69-7(Hazardous Substances Data)

Upstream product

• 25343-70-8 2,6-diisopropylphenyl isothiocyanate 
• 645-36-3 2,2-diethoxy-ethanamine 
• 24544-04-5 2,6-diisopropylbenzenamine 

Downstream Products

• 369657-24-9 1-((((S)-4',5'-dihydro-2'-(1-adamantyl)-4'-oxazolyl)ethyl)-3-(2,6)-diisopropylphenyl)imidazolium iodide 
• 369657-22-7 1-((((S)-4',5'-dihydro-2'-(diphenylmethyl)-4'-oxazolyl)ethyl)-3-(2,6)-diisopropylphenyl)imidazolium iodide 
• 369657-21-6 1-((((S)-4',5'-dihydro-2'-phenyl-4'-oxazolyl)ethyl)-3-(2,6)-diisopropylphenyl)imidazolium iodide 
• 369657-23-8 1-((((S)-4',5'-dihydro-2'-(tert-butyl)-4'-oxazolyl)ethyl)-3-(2,6)-diisopropylphenyl)imidazolium iodide 
• 25364-47-0 1-(2,6-diisopropylphenyl)-1H-imidazole 
• 25372-38-7 2-mercapto-1-(2,6-diisopropylphenyl)imidazole 

Relevant articles and documents

Synthesis of amido-N-imidazolium salts and their applications as ligands in suzuki-miyaura reactions: Coupling of hetero- aromatic halides and the synthesis of milrinone and irbesartan

A new catalytic system based on palladium-amido-N-heterocyclic carbenes for Suzuki-Miyaura coupling reactions of heteroaryl bromides is described. A variety of sterically bulky, amido-N-imidazolium salts were synthesized in high yields from the corresponding anilines. This catalytic system effectively promoted Suzuki-Miyaura couplings of heteroaryl bromides and chlorides with a range of boronic acids to give the corresponding aryl compounds in high yield. The yield was increased with increasing steric bulkiness of the substituted group. Especially, 1-(2,6-diisopropylphenyl)-3-N-(2,4,6-tri-tert- butylphenylacetamido)imidazolium bromide (4bc) exhibited 850,000 TON in the coupling reaction of 2-bromopyridine and phenylboronic acid. In addition, pharmaceutical compounds such as milrinone and irbesartan were synthesized via Suzuki-Miyaura coupling using sterically bulky, amido-N-imidazolium salt (4bc) as a ligand. Copyright