25364-67-4Relevant academic research and scientific papers
Synthesis and evaluation of novel α-substituted chalcones with potent anti-cancer activities and ability to overcome multidrug resistance
Riaz, Sharon,Iqbal, Maheen,Ullah, Rahim,Zahra, Rida,Chotana, Ghayoor Abbas,Faisal, Amir,Saleem, Rahman Shah Zaib
, p. 123 - 135 (2019/03/19)
A series of forty α-substituted chalcones were synthesized and screened for their antiproliferative activities against HCT116 (colorectal) and HCC1954 (breast) cancer cell lines. Compounds 5a and 5e were found to be the most potent compounds with GI5
Phosphorous acid functionalized polyacrylonitrile fibers with a polarity tunable surface micro-environment for one-pot C-C and C-N bond formation reactions
Xu, Gang,Wang, Lu,Li, Mengmeng,Tao, Minli,Zhang, Wenqin
supporting information, p. 5818 - 5830 (2017/12/26)
The preparation and application of fiber catalysts have attracted much attention. However, research on the effect of the micro-environment of fiber catalysts on the catalytic activities though of special importance is limited. In this work, a novel strategy for the synthesis of phosphoric acid-functionalized polyacrylonitrile fibers with a polarity tunable surface micro-environment by hydrophobic groups for one-pot C-C and C-N bond formation reactions is reported. The special hydrophobic surface micro-environment of the fiber catalysts is proven to promote the catalytic activities impressively in cyclocondensation of β-ketoesters with 2-aminobenzamides, the Knoevenagel condensation as well as the multi-component Biginelli reactions in green solvents. Both the surface synergy of the catalytic sites and hydrophobic auxiliary groups (benzyl or n-butyl) in the surface of fiber catalysts and interface acceleration in reaction medium play an important role in the highly efficient promotion of catalytic activity. Thereby a surface synergistic mechanism is proposed to explain the micro-environment effect. In addition, the fiber catalysts could be simply separated from the reaction system using tweezers and directly used in the next cycle without further treatment. Importantly, even after 10 reaction cycles in water or ethanol, there is no significant loss in their catalytic activity. The results indicate that the phosphoric acid functionalized fibers show green and sustainable potential for industrial production.
A systematic study on Knoevenagel reaction and Nazarov cyclization of less reactive carbonyl compounds using rare earth triflates and its applications
Ilangovan,Muralidharan,Maruthamuthu
scheme or table, p. 1000 - 1006 (2012/02/05)
A systematic study of Knoevenagel reaction and Nazarov cyclization was made on variety of less reactive carbonyl compounds such as β-ketoesters, 1,3-diketones and cyclic active methylene compounds using Yb(OTf)3 as the catalyst. Recycling study confirms reusability of the catalyst without much loss of activity.
Catalysis by L-lysine: A green method for the condensation of aromatic aldehydes with acidic methylene compounds in water at room temperature
Zhang, Yan,Sun, Cuizhi,Liang, Jun,Shang, Zhicai
experimental part, p. 2255 - 2259 (2011/10/09)
The condensation of aromatic aldehydes with acidic methylene compounds such as ethyl benzoylacetate, 2,4-pentanedione and dimedone proceeded efficiently in pure water in the presence of L-lysine at room temperature. Interestingly, there are two different
ADDITION OF SODIUM BISULFITE TO DERIVATIVES OF ETHYL ESTERS OF α-SUBSTITUTED CINNAMIC ACIDS
Samarenko, V. Ya.,Markova, N. R.,Passet, B. V.
, p. 122 - 127 (2007/10/02)
The reaction of derivatives of ethyl esters of α-substituted cinnamic acids with sodium bisulfite under conditions excluding radical addition gave the corresponding derivatives of 2-R-substituted sodium 1-phenyl-2-ethoxycarbonyl-1-ethanesulfonates.The eff
