25366-21-6 Usage
General Description
4-METHYL-1-(TRIFLUOROACETYL)-3-THIOSEMICARBAZIDE is a chemical compound with the molecular formula C5H6F3N3O2S. It is a thiosemicarbazide derivative that is known for its potential applications in pharmaceutical and biological research. It has been studied for its antibacterial and antifungal properties, as well as its potential use in the synthesis of heterocyclic compounds. The trifluoroacetyl group in the compound contributes to its pharmacological and biological properties, making it a potential candidate for further research and development. Studies have also been conducted on its potential use as a precursor in the synthesis of various organic compounds. Its unique structure and properties make it a subject of interest for researchers in the field of medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 25366-21-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,3,6 and 6 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 25366-21:
(7*2)+(6*5)+(5*3)+(4*6)+(3*6)+(2*2)+(1*1)=106
106 % 10 = 6
So 25366-21-6 is a valid CAS Registry Number.
InChI:InChI=1/C4H6F3N3OS/c1-8-3(12)10-9-2(11)4(5,6)7/h1H3,(H,9,11)(H2,8,10,12)
25366-21-6Relevant articles and documents
Identifying new lead structures to enhance tolerance towards drought stress via high-throughput screening giving crops a quantum of solace
Frackenpohl, Jens,Schneider, Linn,Decker, Luka J.B.,Dittgen, Jan,Fenkl, Franz,Fischer, Christian,Franke, Jana,Freigang, Joerg,Getachew, Rahel,Gonzalez Fernandez-Nino, Susana M.,Helmke, Hendrik,Hills, Martin J.,Hohmann, Sabine,Kleemann, Jochen,Kurowski, Karoline,Lange, Gudrun,Luemmen, Peter,Meyering, Nicole,Poree, Fabien,Schmutzler, Dirk,Wrede, Sebastian
, (2019/11/13)
Novel synthetic lead structures interacting with RCAR/(PYR/PYL) receptor proteins were identified based on the results of a high-throughput screening campaign of a large compound library followed by focused SAR studies of the three most promising hit clusters. Whilst indolinylmethyl sulfonamides 8y,z and phenylsulfonyl ethylenediamines 9y,z showed strong affinities for RCAR/ (PYR/PYL) receptor proteins in wheat, thiotriazolyl acetamides 7f,s exhibited promising efficacy against drought stress in vivo (wheat, corn and canola) combined with confirmed target interaction in wheat and arabidopsis thaliana. Remarkably, binding affinities of several representatives of 8 and 9 were on the same level or even better than the essential plant hormone abscisic acid (ABA).