25379-15-1Relevant academic research and scientific papers
Syntheses of 7H-pyrido- and 7H-pyrano[2,3,4-kl]acridin-2(3H)-ones from 9-chloroacridines
Gorelik,Titova,Gordievskaya
, p. 1664 - 1669 (2006)
A method for peri-annulation of the pyridine or pyran ring to acridine was developed and used to obtain 7H-pyrido-and 7H-pyrano[2,3,4-kl]acridin-2(3H)- ones. The peri-groups were formed by a reaction of 9-chloro-1-nitroacridine with a CH-acid (malononitri
Synthesis of acridine-quinone systems - A potential electrochemical fluorescent switch
Litchfield, Verity J.,Smith, Robert B.,Franklin, Anthony M.,Davis, James
, p. 3447 - 3455 (2008/12/23)
The synthesis of various acridine-quinones is reported. The fluorescence-quenching quinone moiety has been incorporated into various acridine molecules, each having a different functionality at the ninth position of the acridine ring. It is envisaged that
Synthesis of ascididemine and an isomer
Alvarez, Mercedes,Feliu, Lidia,Ajana, Wadi,Joule, John A.,Fernandez-Puentes, Jose Luis
, p. 849 - 855 (2007/10/03)
Ascididemine (9H-quino[4,3,2-de][1,10]phenanthrolin-9-one) (1) and an isomer (9H-quino[4,3,2-de][1,7]phenanthrolin-9-one) (4) have been synthesized starting from 1,4-dimethoxyacridone (7). The acridone was converted into 1,4- dimethoxy-9-ethynylacridine (
Synthesis of benzacridine and pyridoacridine via Diels-Alder reaction of acridonequinone
Horiguchi, Yoshie,Sakuma, Shinichi,Suzuki, Hideki,Sano, Takehiro
, p. 1305 - 1316 (2007/10/03)
Synthesis of benz[b]acridones (8) and pyrido[3,2-b]acridones (15) was achieved by Diels-Alder reaction of acridonequinones (5) with several activated 1,3-dienes. The addition proceeded in a regioselective manner under mild conditions, thus providing a con
Structure-trypanodical activity relationships
Bsiri,Johnson,Kayirere,Galy,Galy,Barbe,Osuna,Mesa-Valle,Castilla Calvente,Rodriguez-Cabezas
, p. 27 - 33 (2007/10/03)
A set of 9-thioalkylacridinones, has been prepared and investigated' in vitro' against T. cruzi. Structure-antiparasitic activity relationships are detailed with a view to identify the major structural parameters for the activity under consideration.
Use of N-lithiated ethyl anthranilates as 1,4-dipole equivalents in 1,4-dipole-aryne cycloaddition: a novel approach to the synthesis of acridones
Khanapure,Bhawal,Biehl
, p. 2869 - 2972 (2007/10/02)
A new strategy for acridones based on 1,4-dipolar cycloaddition of N-lithiated ethyl anthranilates, which function as 1,4-dipole equivalents, with arynes is reported.
