254112-89-5Relevant academic research and scientific papers
α-alkyl-α-amino-β-lactam peptides: Design, synthesis, and conformational features
Palomo, Claudio,Aizpurua, Jesus M.,Benito, Ana,Galarza, Regina,Khamrai, Uttam K.,Vazquez, Jordi,De Pascual-Teresa, Beatriz,Nieto, Pedro M.,Linden, Anthony
, p. 3056 - 3058 (2007/10/03)
Remarkable asymmetric induction is achieved in the alkylation of the lithium enolate of the β-lactam 1. This allows the first time access to a new family of peptidomimetics 2 with predictable conformational constraints.
