2544-92-5Relevant articles and documents
Nickel(ii)-catalyzed addition of aryl-, alkenyl-, and alkylboronic acids to alkenylazaarenes
Liu, Xing-Yu,Tan, Yun-Xuan,Wang, Xin,Xu, Hao,Wang, Yu-Hui,Tian, Ping,Lin, Guo-Qiang
supporting information, p. 4038 - 4042 (2020/05/18)
A nickel(II)-catalyzed addition of aryl-, alkenyl-, and alkylboronic acids to alkenylazaarenes was presented. This reaction exhibited high efficiency (up to 93% yield), a broad substrate scope (seven types of heterocycles), and good functional group compatibility. The resulting products can be further transformed to many useful building blocks. Finally, the preliminary studies suggested that the adjacent N atom of the heterocycles was essential for the high reactivity.
Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines
Smith, Joshua J.,Best, Daniel,Lam, Hon Wai
supporting information, p. 3770 - 3772 (2016/03/22)
Cu-catalyzed three-component couplings of vinylazaarenes, B2(pin)2, and N-Boc imines are described. Oxidation of the initially formed boronate gives azaarene-containing, Boc-protected amino alcohols with reasonable to good diastereoselectivities.
Enantioselective copper-catalyzed reductive coupling of vinylazaarenes with n -boc aldimines
Choi, Bonnie,Saxena, Aakarsh,Smith, Joshua J.,Churchill, Gwydion H.,Lam, Hon Wai
supporting information, p. 350 - 354 (2015/02/19)
The diastereo- and enantioselective reductive coupling of vinylazaarenes with N-Boc aldimines is described. The reactions proceed using chiral copper-bisphosphine complexes in the presence of TMDS as a hydride source to give reductive coupling products in moderate to high enantioselectivities.
