25468-67-1

Basic information

• Product Name: BenzenepropanaMide, 4-fluoro-
• Synonyms: BenzenepropanaMide, 4-fluoro-;p-fluorobenzenepropanamide
• CAS NO: 25468-67-1
• Molecular Formula: C₉H₁₀FNO
• Molecular Weight: 167.1802032
• Mol File: 25468-67-1.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BenzenepropanaMide, 4-fluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: BenzenepropanaMide, 4-fluoro-(25468-67-1)
• EPA Substance Registry System: BenzenepropanaMide, 4-fluoro-(25468-67-1)

Safety Data

• Hazardous Substances Data: 25468-67-1(Hazardous Substances Data)

Upstream product

• 405-99-2 para-fluorostyrene 
• 77287-34-4 formamide 
• 459-57-4 4-fluorobenzaldehyde 
• 136265-10-6 ethyl 4-fluorocinnamate 
• 201230-82-2 carbon monoxide 
• 772-70-3 3-(4-fluorophenyl)propanoyl chloride 
• 459-31-4 3-(4-fluorophenyl)propanoic acid 
• 459-32-5 (E)-4-fluorocinnamic acid 

Downstream Products

• 25468-86-4 3-(4'-fluorophenyl)propanenitrile 
• 101488-65-7 3-(4-fluorophenyl)propan-1-amine 
• 852660-37-8 N-((1R,2S)-2-{[tert-butoxycarbonyl[3-(4-fluorophenyl)propyl]amino]methyl}cyclohexyl)-N'-[3-(1-methyl-1H-tetrazol-5-yl)phenyl]urea 
• 852660-36-7 (1R,2S)-2-({tert-butoxycarbonyl-[3-(4-fluorophenyl)-propyl]amino}-methyl)-cyclohexylamine 
• 852660-32-3 N-((1R,2S)-2-{[[3-(4-fluorophenyl)propyl]amino]methyl}cyclohexyl)-N'-[3-(1-methyl-1H-tetrazol-5-yl)phenyl]urea 
• 852661-55-3 N-((1R,2S)-3-{ethyl[3-(4-fluorophenyl)propyl]amino}-2-hydroxy-1-methylpropyl)-N'-[3-(1-methyl-1H-tetrazol-5-yl)phenyl]urea 
• 852661-54-2 (2S,3R)-3-amino-1-{ethyl[3-(4-fluorophenyl)propyl]amino}butan-2-ol 
• 46459-22-7 2-(4-fluoro-phenethyl)-5,6-dihydro-4H-[1,3]thiazine 

Relevant articles and documents

Identification of 2,6-Disubstituted 3 H-Imidazo[4,5- b]pyridines as Therapeutic Agents for Dysferlinopathies through Phenotypic Screening on Patient-Derived Induced Pluripotent Stem Cells

Dysferlinopathies, which are muscular diseases caused by mutations in the dysferlin gene, remain serious medical problems due to the lack of therapeutic agents. Herein, we report the design, synthesis, and structure-activity relationships of a 2,6-disubst

Palladium-catalyzed regiodivergent hydroaminocarbonylation of alkenes to primary amides with ammonium chloride

Palladium-catalyzed hydroaminocarbonylation of alkenes for the synthesis of primary amides has long been an elusive aim. Here, we report an efficient catalytic system which enables inexpensive NH4Cl to be utilized as a practical alternative to gaseous ammonia for the palladium-catalyzed alkene-hydroaminocarbonylation reaction. Through appropriate choice of the palladium precursors and ligands, either branched or linear primary amides can be obtained in good yields with good to excellent regioselectivities. Primary mechanistic studies were conducted and disclosed that electrophilic acylpalladium species were capable of capturing the NH2-moiety from ammonium salts to form amides in the presence of CO with NMP as a base.

Compounds with cardiac myosin activating function and pharmaceutical composition containing the same for treating or preventing heart failure

Disclosed are a compound having cardiotonic activity and a pharmaceutical composition containing the same, and the composition containing the compound, according to the present invention, is useful for preventing and treating heart failure.COPYRIGHT KIPO 2016